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Company Information:

Company Name: CYTEX THERAPEUTICS INC.
City: DURHAM
State: NC
Zip+4: 27715-1317
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $497,952.00 2
STTR Phase I $1,098,036.00 4
STTR Phase II $2,442,371.00 2

Award List:

Hip Joint Resurfacing with Functional Human Cartilage

Award Year / Program / Phase: 2007 / STTR / Phase I
Agency: HHS
Research Institution: MASSACHUSETTS INSTITUTE OF TEC
Principal Investigator: Lisa E. Freed
Award Amount: $236,632.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Degenerative joint disease accounts for substantial human suffering at tremendous social and economic cost. While prosthetic joint replacement is a well-established procedure, a finite life span makes this treatment una cceptable for younger or active individuals… More

Hybrid Composite Scaffolds for Cartilage Tissue Engineering

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Geoffrey R. Erickson
Award Amount: $198,625.00
Abstract:
DESCRIPTION (provided by applicant): Damage and subsequent degeneration of articular cartilage in the form of osteoarthritis represents a major health issue globally, and current estimates report that by the year 2020, over 59 million Americans will be dia gnosed with arthritis. As treatment options… More

Functional Tissue Engineering for Cartilage Repair

Award Year / Program / Phase: 2009 / STTR / Phase I
Agency: HHS
Research Institution: DUKE UNIVERSITY
Principal Investigator: Farshid Guilak
Award Amount: $261,996.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Degenerative joint diseases such as osteoarthritis remain the source of significant pain and disability, affecting 20 million adults with an economic burden of over 40 billion per year to the United States. While join t replacement is a well-established… More

Hip-Joint Resurfacing with Functional Human Cartilage

Award Year / Program / Phase: 2010 / STTR / Phase II
Agency: HHS
Research Institution: Charles Stark Draper Laboratory
Principal Investigator: Lisa E. Freed – 617-452-2603
Award Amount: $1,139,179.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Degenerative joint disease accounts for substantial human suffering at tremendous social and economic cost. While prosthetic joint replacement is a well-established procedure, a finite life span makes this treatment unacceptable for younger or active individuals… More

A crosslinked cartilage-derived matrix for cartilage tissue engineering

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bradley T. Estes – 919-912-9839
Award Amount: $299,327.00
Abstract:
DESCRIPTION (provided by applicant): The treatment of injuries or diseases affecting articular or elastic cartilage poses important unmet challenges to the medical community. The goal of this Phase I SBIR is to further the development of a method for themanufacture of a biologically-derived… More

Osteochondral tissue repair in an ovine model using a 3D woven poly (e-caprolacto

Award Year / Program / Phase: 2013 / STTR / Phase I
Agency: HHS
Research Institution: COLORADO STATE UNIVERSITY
Principal Investigator: Bradley T. Estes – 919-912-9839
Award Amount: $299,744.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Standard microfracture is a first-line, widely used and cost-effective surgical technique for repairing damaged articular cartilage, but, it is limited by decreased long-term efficacy and limited applicability in largerlesions. This leads to a burgeoning economic… More

Controlling mechanical signal transduction to treat osteoarthritis

Award Year / Program / Phase: 2013 / STTR / Phase I
Agency: HHS
Research Institution: DUKE UNIVERSITY
Principal Investigator: Wolfgang B. Liedtke – 919-684-0058
Award Amount: $299,664.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Controlling mechanical signal transduction to treat osteoarthritis Abstract The TRPV4 calcium (Ca++) permeable ion channel has been shown to be expressed and functional in chondrocytes, the cells responsible for the maintenance of cartilage in weight-bearing… More

Functional Tissue Engineering for Cartilage Repair

Award Year / Program / Phase: 2013 / STTR / Phase II
Agency: HHS
Research Institution: DUKE UNIVERSITY
Principal Investigator: Farshid Guilak – 919-684-2521
Award Amount: $1,303,192.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this study is to develop a tissue-engineered total joint replacement from an engineered biomaterial scaffold combined with adult bone marrow-derived mesenchymal stem cells (MSCs) for regeneration ofthe entire femoral surface of the hip joint.… More