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Company Information:

Company Name: CYTOCURE, LLC
City: BEVERLY
State: MA
Zip+4: 01915-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $950,786.00 5

Award List:

REVERSAL OF 'ANTIGEN-SILENCING' FOR CANCER THERAPY

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Paul J. Durda
Award Amount: $250,000.00
Abstract:
DESCRIPTION: (Applicant's Description) oxide synthase; iNOS) has been implicated in the pathogenesis of various forms of inflammation. Chronic inflammation is a known risk factor for carcinogenesis. There are multiple lines of… More

GFP-REPORTER CONSTRUCTS FOR TUMOR ANTIGEN REGULATION

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ian S. Dunn
Award Amount: $168,700.00
Abstract:
The goals of this Phase I project are to develop stable melanoma cell lines containing a reporter gene linked to the Melan-NMART-1 promoter for use in high throughput drug screening. We propose to develop these cell lines to identify drugs that up-regulate Melan-A/MART-1 expression. Loss of tumor… More

TRANSCRIPTION REGULATION OF MELANOMA ANTIGEN EXPRESSION

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ian S. Dunn
Award Amount: $100,000.00
Abstract:
DESCRIPTION (provided by applicant): The overall aim of this Phase I proposal is to devise therapeutic modalities which will assure constitutive expression of antigenic proteins needed for effective cell-mediated immunity against the tumor cells. These studies will focus on the regulation of genes… More

HTS for agents that increase recognition of tumors by cytotoxic lymphocytes

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Timothy J. Haggerty
Award Amount: $132,086.00
Abstract:
DESCRIPTION (provided by applicant): The ultimate aim of this proposal is to design improved therapies for malignant melanoma. This proposal will promote the development of a High Throughout Screening (HTS) system for assessing cell mediated cytotoxicity a gainst human tumor cells, which is a… More

Combination Melanoma Immunotherapy: Antigen Enhancement and Adoptive T Cells

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Estelle E. Newton – 978-232-1243
Award Amount: $300,000.00
Abstract:
DESCRIPTION (provided by applicant): The ultimate goal of this proposal is to develop agents to increase the efficacy of immunotherapy of malignant melanoma. The studies in this proposal involve a proof-of-principle combination immunotherapy protocol in amouse model, using drugs to increase antigen… More