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PROTECTIVE TREATMENT FOR CATHETERS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7321
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
7321
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Denver Surgical Developments
6851 Highway 73 Evergreen, CO 80439
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1987
Title: PROTECTIVE TREATMENT FOR CATHETERS
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE LONG-TERM OBJECTIVE OF THIS RESEARCH IS TO MAKE COMMERCIALLY AVAILABLE CENTRAL VENOUS CATHETERS (CVC) THAT HAVE BEEN CHEMICALLY TREATED TO REDUCE THEIR TENDENCY TO INDUCE INFECTIONS, THEREBY BRINGING MAJOR HUMANITARIAN BENEFITS AND SUBSTANTIAL REDUCTIONS IN HOSPITAL CARE COSTS. SPECIFICALLY, DENVER SURGICAL DEVELOPMENTS, INC. WILL: (1) APPLY AN ALREADY DEVELOPED PROCESS FOR ANTIMICROBIAL PROTECTION OF SILICONE RUBBER TO A COMMONLY USED CVC (HICKMAN) DEVICE; (2) DETERMINE THE DURATION AND LEVELS OF ANTIMICROBIAL ACTIVITY OF OPTIMALLY TREATED CATHETERS DURING PERFUSION WITH SALINE, NUTRITIONAL, AND ONCOTHERAPEUTIC SOLUTIONS; (3) DETERMINE THE DEGREES OF PROTECTION OF TREATED CATHETERS AGAINST LUMEN COLONIZATION IN VITRO; (4) DETERMINE THE BIOCOMPATIBILITY IN MOUSE TISSUE OF THE TREATED CATHETER MATERIAL; AND (5) DETERMINE THE EFFECTS OF NORMAL STORAGE ON ANTIBACTERIAL ACTIVITY AND TENSILE STRENGTH OF TREATED CATHETERS.

Principal Investigator:

John b newkirk d sc
3036745294

Business Contact:

Small Business Information at Submission:

Denver Surgical Developments
6851 Highway 73 Evergreen, CO 80439

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No