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Array microscope image-acquisition system

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
66532
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
GM069117
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
DMETRIX, INC.
9030 South Rita Rd Ste 389 TUCSON, AZ -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2003
Title: Array microscope image-acquisition system
Agency: HHS
Contract: 1R43GM069117-01
Award Amount: $107,039.00
 

Abstract:

DESCRIPTION (provided by applicant): DMetrix is developing an innovative array-microscope slide scanner to generate virtual slides in histopathology. The innovation consists of the use of an array of miniaturized objectives, each measuring approximately 2 mm in diameter and 10 mm in length, slightly staggered in the array, to produce a single, seamless sweep of the microscope slide. The combination of the array microscope optics and the image acquisition system proposed here will allow very rapid scanning, requiring less than 12 seconds for a full microscope slide of 20 mm x 50 mm, at diffraction-limited sampling, The proposed image-acquisition system consists of an optimized, high-speed CMOS image sensor operating at 60 MHz with eight (8) parallel outputs and the accompanying high-speed electronics. The CMOS image sensor is optimized to match the format of the array-microscope optics. The proposed highspeed electronics will be designed to control the image sensor, digitize the image sensor's analog outputs, process the image data in real-time, and compress the image data prior to storage on a host personal computer (PC). The array-microscope virtual-slide scanner will allow digitization of slides at rates 50 times faster than conventional single-optical-axis optical systems. Applications of such a virtual slide scanner are to be found in histopathology, telepathology, pathology education, and pharmaceutical research.

Principal Investigator:

Pixuan Zhou
5207229510
JZHOU@DMETRIX.COM

Business Contact:

Michael Descour
5207229510
DESCOUR@DMETRIX.COM
Small Business Information at Submission:

DMETRIX, INC.
DMETRIX, INC. 1141 W GRAND RD, STE100 TUCSON, AZ 85705

EIN/Tax ID: 861036587
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No