A feasability study is being conducted toward development ofa stand-alone database product for personal computers featuring linked access to multiple databases of interest to molecular biologists. all data and access software will be located on a compact disk so that no connection to external… More

Large-scale dna sequence efforts have resulted in knowledge of the amino acid sequences of a large number of proteins, many of which have no known function. because x-ray crystallography and other physical and biochemical methods for characterizing proteins are laborious and slow, there is great… More

The overall objective of this research is to develop a highly automated dna sequencing system that can be sold to molecular biology researchers interested in carrying out large-scale sequencing projects. the complete system will include robotic reaction preparation, a high-capacity gel… More

The overall objective of this research is to develop a highly automated dna sequencing system that can be sold to molecular biology researchers interested in carrying out large scale sequencing projects. the complete system will include robotic reaction preparation, high capacity gel electrophoresis… More

The advent of genome analysis through molecular biology has brought into prospect thecomplete sequence analysis of the human genome and other species. The data is being gathered at anever increasing rate and the ways in which they will be analyzed are evolving even as it is beingcollected. The… More

This grant will improve the software for DNA sequencing by integrating the components of basecalling, sequence assembly and post-assembly analysis into an integrated software system. To test theperformance of the software configurations, data for known regions of E. coli will be resequenced fromthe… More

Not Available The project by Micro Analysis & Design, Inc. presented in this proposal involves the design and demonstration of a Measure of Performance (MOP) based assessment system. The measurement approach is based on a probabilistic reasoning method using Bayesian networks. A set of three… More

APPLICANT?S DESCRIPTION: This proposal presents a plan to design and produce a software product for DNA fragment assembly that meets the needs of large-scale sequencing efforts. The effort demands software that is fast and highly accurate. DNASTAR?s proposed product will meet the needs through… More

APPLICANT?S DESCRIPTION: This proposal presents a plan to design and produce a software product for DNA fragment assembly that meets the needs of large-scale sequencing efforts. The effort demands software that is fast and highly accurate. DNASTAR?s proposed product will meet the needs through… More