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ARTIFICIAL INTELLIGENCE SYSTEM FOR ANALYSIS OF PROTEINS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
11280
Program Year/Program:
1990 / SBIR
Agency Tracking Number:
11280
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
DNASTAR, INC.
1228 S PARK ST MADISON, WI 53715
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1990
Title: ARTIFICIAL INTELLIGENCE SYSTEM FOR ANALYSIS OF PROTEINS
Agency: HHS
Contract: N/A
Award Amount: $500,000.00
 

Abstract:

LARGE-SCALE DNA SEQUENCE EFFORTS HAVE RESULTED IN KNOWLEDGE OF THE AMINO ACID SEQUENCES OF A LARGE NUMBER OF PROTEINS, MANY OF WHICH HAVE NO KNOWN FUNCTION. BECAUSE X-RAY CRYSTALLOGRAPHY AND OTHER PHYSICAL AND BIOCHEMICAL METHODS FOR CHARACTERIZING PROTEINS ARE LABORIOUS AND SLOW, THERE IS GREAT INTEREST IN THE USE OF COMPUTERS TO HELP DETERMINE STRUCTURAL CORRELATES OF FUNCTION AND TO ASCERTAIN RELATIONSHIPS BETWEEN KNOWN PROTEINS AND UNKNOWN ONES. RECENT PROGRESS HAS BEEN MADE BY THE APPLICATION OF ARTIFICIAL INTELLIGENCE TECHNIQUES, RESULTING IN A PROTEIN ANALYSIS SYSTEM KNOWN AS ARIADNE. THIS RESEARCH WILL EXPLORE THE FEASIBILITY OF IMPLEMENTING ARIADNE IN A FORM THAT CAN BE USED BY INDIVIDUAL LABORATORIES AND SCIENTISTS ON PERSONAL COMPUTERS OR WORKSTATIONS. IT IS PLANNED TO IMPLEMENT ARIADNE ON A PERSONAL COMPUTER, PROVIDE IT WITH A USER-FRIENDLY INTERFACE AND SEAMLESS ACCESS TO MOLECULAR DATABASES, AND EVALUATE ITS PERFORMANCE.

Principal Investigator:


0

Business Contact:

Small Business Information at Submission:

Dnastar Inc.
1228 S Park St Madison, WI 53715

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No