Data Driven Sequence Assembly

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 25116	Program Year/Program: 1994 / SBIR
Agency Tracking Number: 25116	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: DNASTAR, INC.
1228 S PARK ST MADISON, WI 53715
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 1: Fiscal Year: 1994

Title: Data Driven Sequence Assembly

Agency: HHS

Contract: 1 R43 GM51680-1,

Award Amount: $75,000.00

Abstract:
This grant will improve the software for DNA sequencing by integrating the components of basecalling, sequence assembly and post-assembly analysis into an integrated software system. To test theperformance of the software configurations, data for known regions of E. coli will be resequenced fromthe original clones using a LI-Cor sequencing instrument. The data will be basecalled by neural net basedpattern recognition and assembled with a variety of multiple alignment methods. Algorithmic solutionswill be compared and evaluated relative to the goal of achieving an accurate final sequence with theminimum of editing by a human expert. Alleviating the need for sequence editing will present theopportunity for significant cost savings in genome projects and other research involving DNA sequencing.

Principal Investigator:
Schuyler Baldwin
6082587420

Business Contact:

Small Business Information at Submission:

Dnastar, Inc.
1228 S Park Street Madison, WI 53715

EIN/Tax ID:

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No