DESCRIPTION (provided by applicant): The aim of this program is to develop a low-cost, easy-to-use instrument to measure the blood flow in artificial dialysis access grafts. With such an instrument, these grafts could be monitored at frequent enough intervals to detect the falling flow levels that… More

DESCRIPTION (provided by applicant): The aim of this program is to develop an instrument suitable for screening the carotid artery for stenoses that lead to stroke. In the last decade it was shown that removal of high grade carotid stenoses could reduce the stroke rate in that population by more… More

DESCRIPTION (provided by applicant): Development of a self-monitoring graft is the long term goal of this project. Such a graft, rather than being a passive conduit for blood, would measure the blood flowing through it and, if the flow approached levels at which the graft might thrombose,… More

DESCRIPTION (provided by applicant): Most artificial vascular grafts, of which 60,000 were implanted in the USA last year, fail in less than three years, leading to amputation. Diminishing blood flow through the graft has been shown to be a precursor of raft failure. The long-term objective of… More

DESCRIPTION (provided by applicant): The aim of this program is to develop and bring to commercialization a new ultrasound Doppler device to be used to monitor the flow in dialysis access grafts. By detecting falling flow before the graft thromboses, this instrument can significantly reduce the… More

DESCRIPTION (provided by applicant): The aim of this program is to develop and bring to commercialization a new ultrasound Doppler device to be used to monitor the flow in dialysis access grafts. By detecting falling flow before the graft thromboses, this instrument can significantly reduce the $1… More

DESCRIPTION (provided by applicant): The goal of this program is to reduce the occurrence of stroke. This leading cause of disability, and third leading cause of death, strikes without warning in 80% of cases; finding and correcting the conditions that lead to stroke can prevent stroke. At least… More

DESCRIPTION (provided by applicant): Without blood, tissue dies. The goal of this project is to develop very small sensors - looking something like this, -- that can be placed flat on the wall of a blood vessel and measure its blood flow. This new device i s called a patch-sensor, and this STTR… More

DESCRIPTION (provided by applicant): Over a million minimally invasive procedures to preserve blood flow - angioplasties, stent placements, thrombectomies - are performed each year in the United States. The goal of this program is to provide means of measu ring blood flow in these vessels during and… More

DESCRIPTION (provided by applicant): This research is to develop a minimally invasive, percutaneously-placed system that will measure blood flow in the body. Blood flow keeps tissue alive. Sophisticated instruments, such as duplex Doppler, MRI or CT angiog raphy, can measure blood flow… More

DESCRIPTION (provided by applicant): Several hundred thousand people in the USA each year require artificial blood vessels,  grafts , to be placed in their legs because of failing circulation. Sixty thousand of these patients require artificial prosthetic grafts. Unfortunately, many of the… More

DESCRIPTION (provided by applicant): Minimally invasive treatments using catheters to correct a serious cardiovascular problem has revolutionized cardiovascular care. Almost a million such procedures take place each year in the United States. These procedures are guided by X-ray visualization of the… More