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Company Information:

Company Name: ISOTHERAPEUTICS GROUP, LLC
City: Angleton
State: TX
Zip+4: 77515-5250
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $293,058.00 2
SBIR Phase II $989,748.00 1

Award List:

A new radiopharmaceutical for the treatment of metastatic bone cancer

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jaime N. Simon
Award Amount: $143,582.00
Abstract:
DESCRIPTION (provided by applicant): Bone-seeking radiopharmaceuticals are used extensively for bone pain palliation and have shown promise for treating bone metastases. They typically combine a radioactive metal such as samarium-153 with a chelator. The chelator part of the molecule is taken up… More

High Specific Activity Sm-153 by Post Irradiation Isotope Separation

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: DOE
Principal Investigator: Jaime Simon, Dr. – 979-848-0800
Award Amount: $149,476.00
Abstract:
When the stable samarium-152 (Sm-152) isotope is irradiated, radioactive samarium-153 (Sm-153) is produced through a neutron capture reaction in yields of only about 2%, and this radioactive, therapeutic isotope (Sm-153) cannot be separated from the much more abundant (~98%) non-radioactive isotope… More

High Specific Activity Sm-153 by Post Irradiation Isotope Separation

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: DOE
Principal Investigator: Jaime Simon, Dr. – 979-848-0800
Award Amount: $989,748.00
Abstract:
Samarium-153 (153Sm) has ideal nuclear properties for a variety of therapeutic applications; however, it is only available in low specific activity (radioactivity/weight) form. While large quantities can be made by the 152Sm(n,)153Sm reaction in a medium flux reactor such as at the University… More