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A NEAR-INFRARED FIBEROPTICALLY COUPLED RAMAN SPECTROMETER

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
13881
Program Year/Program:
1990 / SBIR
Agency Tracking Number:
13881
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
EIC LABORATORIES, INC.
111 DOWNEY ST NORWOOD, MA 02062-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1990
Title: A NEAR-INFRARED FIBEROPTICALLY COUPLED RAMAN SPECTROMETER
Agency: HHS
Contract: N/A
Award Amount: $499,974.00
 

Abstract:

THE OBJECTIVE OF THIS PROGRAM IS TO DEVELOP A LOW-COST, FIBEROPTICALLY COUPLED RAMAN SPECTROMETER FOR BIOLOGICAL, BIOCHEMICAL, BIOPHYSICAL, AND CLINICAL APPLICATIONS. RAMAN SPECTROSCOPY PROVIDES MOLECULAR FINGERPRINTING CAPABILITIES AS DOES INFRARED SPECTROSCOPY, BUT UNLIKE INFRARED, RAMAN ISAPPLICABLE TO AQUEOUS ENVIRONMENTS. THE PROPOSED INSTRUMENTWILL PROVIDE THE SCIENTIFIC COMMUNITY WITH A FLEXIBLE AND EASIER METHOD OF OBTAINING RAMAN SPECTRA FOR BOTH DEDICATED AND GENERAL LABORATORY APPLICATIONS THAN CURRENT COMMERCIAL RAMAN SPECTROMETERS (BOTH VISIBLE AND FT-RAMAN). THE PHASE I OBJECTIVE IS TO DEMONSTRATE A PROTOTYPE FIBEROPTICALLY COUPLED INSTRUMENT IN A BREADBOARD CONFIGURATION. COST SAVINGS AS WELL AS SIZE REDUCTION OF THE INSTRUMENT WILL BE ACCOMPLISHED WITH A NEW SPECTROMETER DESIGN BASED ON THE HADAMARD TRANSFORM MULTIPLEXING TECHNIQUE AND NEAR-INFRARED EXCITATION (NIR). NIR EXCITATION ALSO RESULTS IN A LOW BACKGROUND FLUORESCENCE ANDREDUCED SAMPLE PHOTODECOMPOSITION. THE EASE AND FLEXIBILITYWILL BE ACHIEVED WITH A FIBEROPTIC DELIVERY AND COLLECTION PROBE DESIGNED SPECIFICALLY FOR NIR RAMAN SPECTROSCOPY. PHASE II WOULD HAVE THE GOAL OF DEVELOPING AND TESTING A TURNKEY INSTRUMENT UTILIZING COMPACT SOLID-STATE LASER SOURCES AND A FIBEROPTIC EXCITATION/COLLECTION SYSTEM.

Principal Investigator:

Michael M Carrabba
6177699450

Business Contact:

Small Business Information at Submission:

Eic Laboratories Inc
111 Downey St Norwood, MA 02062

EIN/Tax ID: 042497074
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No