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Rapid Nondestructive Analysis of Opioid Peptide Purity

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
24984
Program Year/Program:
1994 / SBIR
Agency Tracking Number:
24984
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
EIC LABORATORIES, INC.
111 DOWNEY ST NORWOOD, MA 02062-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1994
Title: Rapid Nondestructive Analysis of Opioid Peptide Purity
Agency: HHS
Contract: 1 R43 DA09216-1,
Award Amount: $80,248.00
 

Abstract:

This project is to develop an analytical instrument and associated protocols for the rapid,nondestructive measurement of molecular and optical purity of the opioid peptides. The instrument willutilize Raman spectroscopy for determination of molecular purity and Raman optical activity (ROA) fordetermination of enantiomeric purity. ROA provides structure-specific optical purity of singlecomponents in the presence of chiral or achiral impurities and is a nondestructive technique. Raman andROA spectroscopy can uniquely determine the purity of the major component as well as uniquely identifyand quantify the impurities that may be present. Phase I objective is to demonstrate the analyticalfeasibility of Raman and ROA spectroscopy for determination of optical and molecular purity of an opioidpeptide. The Phase II objective will be to develop a complete spectral library for all the opioid peptidescurrently stocked by NIDA and to provide NIDA with a prototype ROA instrument.

Principal Investigator:

Kevin Spencer
6177699450

Business Contact:

Small Business Information at Submission:

Eic Laboratory, Inc.
111 Downey Street Norwood, MA 02062

EIN/Tax ID: 042497074
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No