The research would develop an inexpensive electroencephalographic (EEG) amplifier system suitable for dense (128 or 256) electrode arrays. These arrays would provide the measurements necessary for new source localization algorithms constrained by MRI data that image the electrical activity of the… More

Recent studies show that the analysis of the brain's electrical fields with the electroencephalogram (EEG) could produce an informative, cost-effective method of neuroimaging if the density of scalp electrodes were increased substantially over conventional practice. We propose to commercialize an… More

Advances in dense sensor array measurement of brain electrical activity promise new insights into tthe human brain. This project develops Sourcerer(R), an innovative software package for distributedanalysis of Electroencephalographic (BEG) and Event-Related Potential (BRP) data. Whereas… More

Diagnosis of neurological disorders such as epilepsy may soon be improved by the technical advancesarray magnetoencephalography (MEG) and electroencephalography (EEG) (Wikswo, et al. 1993). A relevanof rationed medical care is that the EEG is 10 to 100 times less expensive than the MEG or any… More

Measurement of the human brain's electrical fields at the scalp surface has recently been advancedarray technologies. Imaging of these surface electrical fields has become important for both medicalapplications. Even as new methods for source localization in brain tissues are developed, they… More

Advances in dense sensor array EEG, anatomical imaging of head tissues, and mathematical insights iinverse problems have opened the possibility of a breakthrough in analyzing and imaging the brain'sThe barrier to progress is now the lack of a clear criterion measure for when a solution is… More

Diagnosis of neurological disorders such as epilepsy may soon be improved by the technical advancesarray magnetoencephalography (MEG) and electroencephalography (EEG) (Wikswo, et al. 1993). A relevanof rationed medical care is that the EEG is 10 to 100 times less expensive than the MEG or any… More

Not Available The objective of the proposal is to demonstrate the feasibility of a new LIDAR for remote sensing of optical turbulence and cirrus clouds aboard the Airborne Laser platform. The LIDAR employs common transmit/receive apertures, a pulse laser, and a range gated receiving system, and it… More

Not Available Over 1/3rd of children, particularly children from low-income families, enter kindergarten unable to keep up with their peers. SBIR R&D will develop, test and refine an interactive, video/electronic media program to engage low-income preschoolers in highly motivating, play techniques,… More

Not Available NASA has expressed a need for innovative fabrication methods for diffractive optical elements (DOE's). Such innovations are needed to fully exploit the inherent possibilities of DOE's to increase performance and to reduce the size, weight, and cost of opt

Not Available NASA has determined that Planetary Aerobots are one of the best lightweight vehicles for monitoring the atmosphere (in-situ) and the surfaces (proximally) of Mars, Titan, Venus and outer planets for extended periods of time. Traditional materials unfortun

Not Available The proposed program addresses advanced electrocatalysis for the direct conversion of carbon dioxide into separated methane and oxygen under ambient temperature conditions. This technology will have application in an advanced life support system for carbon dioxide atmospheric control… More

Not Available Silicon carbide has many materials properties that make it desirable for use at extreme temperatures and atmospheres. However the manufacture of complex silicon carbide components as a single piece is both difficult and expensive. Joining technologies ar

DESCRIPTION (provided by applicant): Electroencephalography is a safe, noninvasive technique for monitoring neonatal brain function. Acute and long-term EEG monitoring of infants has clinical utility for evaluating the effects of hypoxic ischemic insults and detecting the presence of… More

DESCRIPTION (provided by applicant): Functional MRI is capable of achieving millimeter spatial resolution in measurements of blood oxygenation associated with neural tissue activation in the brain, while the EEG is capable of achieving sub-millisecond temporal resolution of the electrical activity.… More

DESCRIPTION (provided by applicant): Functional MRI is capable of achieving millimeter spatial resolution in measurements of blood oxygenation associated with neural tissue activation in the brain, while the EEG is capable of achieving sub-millisecond temporal resolution of the electrical activity.… More

In modern military operating environments, military personnel are faced with the challenge of accomplishing more with less human resources. To meet this challenge, each personnel must be able to function optimally. In other words, each operator'scognitive resources must be maximized and delegation… More

This project develops a dense array fNIR/EEG neuroimaging system for use in operational environments. Miniature NIR-enhanced optical emitters and detectors are combined with EEG and EIT (Electrical Impedance Tomography) electrodes embedded in a novel,flexible and wireless, geodesic head web. This… More

In modern military operating environments, military personnel are faced with the challenge of accomplishing more with less human resources. To meet this challenge, each personnel must be able to function optimally. In other words, each operator's cognitive resources must be maximized and delegation… More

Near-infrared light (NIR) can detect intracranial hematomas with good sensitivity and specificity. However, commercial systems have not proved clinically useful. Early detection of hematomas is important for emergency head injury evaluation. The resulting pressure can cause significant brain… More

DESCRIPTION (provided by applicant): Electrophysiologic recording provides inexpensive and non-invasive monitoring of both normal and pathological human brain function. With a saline-sponge technology, a dense array of 64, 128, or 256 electrodes can be applied in a few minutes, allowing… More

DESCRIPTION (PROVIDED BY APPLICANT): Electroencephalography (EEG) is a safe, noninvasive technique for monitoring neonatal brain function. Acute and long-term EEG monitoring of infants has clinical utility for evaluating the effects of hypoxic ischemic insults and detecting the presence of epileptic… More

DESCRIPTION (provided by applicant): Electrophysiologic recording provides inexpensive and non-invasive monitoring of both normal and pathological human brain function. With a saline-sponge technology, a dense array of 64,128, or 256 electrodes can be applied in a few minutes, allowing… More

DESCRIPTION (provided by applicant): The goal of this research is to create custom analog VLSI semiconductor technology to provide a lightweight, compact implementation of a data acquisition system for ambulatory EEG recording using EGFs Geodesic Sensor Net, an electrode system noted for its… More

The integration of NIRS measures with EEG could be a significant advance in rapid detection and continuous monitoring of cerebral dysfunction following traumatic brain injury. We have developed a dense array EEG system that can be applied rapidly in the field environment. We have developed a… More

The integration of NIRS measures with EEG could be a significant advance in rapid detection and continuous monitoring of cerebral dysfunction following traumatic brain injury. We have developed a dense sensor array EEG system that can be applied rapidly in a field environment. We have developed a… More

The integration of NIRS measures with EEG could be a significant advance in rapid detection and continuous monitoring of cerebral dysfunction following traumatic brain injury. We have developed a dense array EEG system that can be applied rapidly in the field environment. We have developed a… More

Based on direction from Dr. Amy Kru

DESCRIPTION (provided by applicant): Electroencephalography (EEG) is an indispensable neurological diagnostic tool in terms of fast time scale, portability, and cost efficiency. Improved spatial resolution of EEG measures would greatly benefit clinical and research applications, including stroke,… More

DESCRIPTION (provided by applicant): This research will create a small and inexpensive multichannel physiological data acquisition system. It will allow dense array (128 or 256 channel) EEG systems to be made at a similar cost as conventional (19 or 32 channels) systems, and it will allow… More

DESCRIPTION (provided by applicant): Electroencephalography (EEG) is a powerful, inexpensive, and underutilized neurodiagnostic tool. Recent technical advances have led to dense-array EEG, with 256-channel sensor nets that can be applied comfortably in 5 minutes, inexpensive, high-performance… More

DESCRIPTION (provided by applicant): The long-term objective of the proposed project is to design a cost-effective, light-weight, integrated, whole- head EEG/NIR brain imaging and data analysis system for non-invasive recording of brain activity in neonate s and young children. This system will… More

DESCRIPTION (provided by applicant): While it is well known that the brain undergoes rapid developmental changes from birth to early childhood, remarkably little is understood about the relationship between changes in brain size and composition and normal cognitive development. Yet we now know that… More

DESCRIPTION (provided by applicant): The long-term objective of the proposed project is to design a low-profile, high-resistive, MRI-compatible dense array EEG sensor net for simultaneous dEEG/fMRI recordings in fields as high as 7 Tesla. This novel sensor net (256-channel InkNet) will use… More

DESCRIPTION (provided by applicant): The goal of this SBIR project is to design a cost-effective, lightweight, integrated, whole-head dense-array electroencephalography and near-infrared spectroscopy (dEEG/NIRS) brain imaging and data analysis system for non-invasive recording of brain activity in… More

The purpose of the proposed work is to demonstrate the feasibility of a novel instrument for multi-channel nuclear Magnetic Resonance Imaging (MRI) at ultra-low field (ULF). The instrument will overcome issues involved with conventional MRI systems use in combat casualty care. It will also provide… More

DESCRIPTION (provided by applicant): Clinical neonatal monitoring is also vital for diagnosis and prognosis of acute pathologies. One such pathology, neonatal intraventricular hemorrhage (IVH), is a common consequence of premature birth, with approximately30 percent of infants weighing less than… More