USA flag logo/image

An Official Website of the United States Government

ELECTROFUSION AND ELECTROPERMEATION OF CELLS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7282
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
7282
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Electrocell
Western Ny Technology Dev Ctr 2211 Main Street Buffalo, NY 14214
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1987
Title: ELECTROFUSION AND ELECTROPERMEATION OF CELLS
Agency: HHS
Contract: N/A
Award Amount: $48,000.00
 

Abstract:

THE TECHNIQUE OF ELECTROPORATION IS UTILIZED TO PERMEATE CELL MEMBRANES TO INTRODUCE DRUGS OR FOREIGN GENETIC MATERIALS INTO LIVING CELLS. ELECTROFUSION IS USED AS A NEWAPPROACH TO FORM HYBRID CELLS FOR GENETICS STUDIES AND FOR MONOCLONAL ANTIBODY PRODUCTION, AS WELL AS FOR DRUG INFUSIONVIA LIPOSOMES. ELECTROCELL PLANS TO DEVELOP PROTOCOLS FOR ELECTROPORATION AND ELECTROFUSION OF COMMON CELL TYPES, BASED ON THE PHYSICAL PROPERTIES OF CELLS. PROTOTYPES OF THE ELECTRONIC CELL FUSER AND PORATOR WILL BE DESIGNED ACCORDING TO ELECTROCELL'S PROTOCOLS. MICROSCOPIC, MACROSCOPIC, AND CONTINUOUS-FLOW CELL-FUSION CHAMBERS WILL BE MADE. THE SUCCESSFUL DEVELOPMENT OF BOTH HARDWARE AND SOFTWARE PROCEDURES AND FORMULAE WILL FORM THE BASIS FOR COMMERCIALIZATION. THE BIOMEDICAL COMMUNITY IN BUFFALO, NEW YORK, PROVIDES AN EXCELLENT ENVIRONMENT FOR BIOTECHNOLOGY TRANSFER AND FEEDBACK, AS WELL AS A TEST MARKET FOR FUTURE EXPANSION.

Principal Investigator:

Hilda liang
7168313472

Business Contact:

Small Business Information at Submission:

Electrocell
Western Ny Technology Dev Ctr 2211 Main Street Buffalo, NY 14214

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No