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SYNTHESIS OF QINGHAOSU ANALOGUES AS POTENTIAL ANTIPARASITIC AGENTS

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
9673
Program Year/Program:
1989 / SBIR
Agency Tracking Number:
9673
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ELECTROSYNTHESIS CO., INC.
72 Ward Road Lancaster, NY 14086
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Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1989
Title: SYNTHESIS OF QINGHAOSU ANALOGUES AS POTENTIAL ANTIPARASITIC AGENTS
Agency / Branch: DOD / ARMY
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE SYNTHESIS OF A SERIES OF QINGHAOSU ANALOGUES AS POTENTIAL ANTIPARASITIC AGENTS IS PROPOSED. THESE MATERIALS WILL INCORPORATE THE UNIQUE LACTONE ENDOPEROXIDE FUNCTION ESSENTIAL FOR THE ACTIVITY OF THE PARENT STRUCTURE. THE SYNTHETIC APPROACHES ARE BASED ON WELL-FOUNDED CHEMICAL PRINCIPLES, UTILIZE INEXPENSIVE STARTING MATERIALS, AND SHOULD PROVIDE THE DESIRED COMPOUNDS IN SUFFICIENT QUANTITIES FOR USAMRDC IN VITRO AND IN VIVO BIOLOGICAL EVALUATION PHASE II WILL EXTEND THESE STUDIES TO DEVELOP EVEN MORE ACTIVE ANALOGUES, AS WELL AS TO PRODUCE LARGER QUANTITIES OF PROMISING COMPOUNDS FOR FURTHER TESTING.

Principal Investigator:

Dr Duane J Mazur
7166840513

Business Contact:

Small Business Information at Submission:

The Electrosynthesis Co Inc
Po Box 430 East Amherst, NY 14051

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No