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Company Information:

Company Name: EMERALD BIOSTRUCTURES,INC.
City: BAINBRIDGE ISLAND
State: WA
Zip+4: 98110-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (206) 780-8535

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,051,790.00 9
SBIR Phase II $1,100,898.00 2

Award List:

ANTICANCER DRUG DESIGN TARGETING HUMAN TOPOISOMERASE I

Award Year / Program / Phase: 1998 / SBIR / Phase I
Agency: HHS
Principal Investigator: Stewart, Lance J
Award Amount: $99,721.00

HIGH THROUGHPUT XRAY STRUCTURES OF MEMBRANE PROTEINS

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lance J. Stewart
Award Amount: $140,453.00
Abstract:
Not Available The use of sled vehicles to perform high speed/high acceleration testing of warheads and warhead components generates an inherently Noisy vibration environment. The anticipated level of shocks and the vibration energy levels associated with sled tracks will normally exceed the… More

ANTICANCER COMPOUNDS DESIGNED TO POISON TOPOISOMERASE I

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lance J. Stewart
Award Amount: $244,348.00
Abstract:
Not Available PhaseSpace proposes to demonstrate in applications, a 3D tracking system that will allow real time interaction of humans in computer generated environments. Tracking active markers will allow control of computer generated characters and objects in real time with less than 10… More

TOOLS FOR COMBINATORIAL MACROMOLECULAR CRYSTALLIZATION

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: Hidong Kim
Award Amount: $97,725.00
Abstract:
Not Available Triton Systems Inc. proposes to use a high strain-rate superplastic forming (HSR-SPF) technology to fabricate complex shaped Nanoparticulate discontinuously reinforced aluminum (DRA) components. Nanoparticulate DRA offers the strength and stiffness advantages of conventional DRA,… More

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lance J. Stewart
Award Amount: $230,608.00

Crystallization Tools for Structural Genomics

Award Year / Program / Phase: 2001 / SBIR / Phase II
Agency: HHS
Principal Investigator: Hidong Kim
Award Amount: $351,960.00
Abstract:
DESCCRIPTION: Applicant?s abstract) An integrated, automated protein crystallization system,RoboHTC (Robotic High-Throughput Crystallization), will be developed, consisting of software and hardware tools suitable for large-scale protein crystallography projects, such as structural genomics. These… More

Anti-Cancer Drug Design Targeting Human Topoisomerase I

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Lance J. Stewart
Award Amount: $0.00
Abstract:
DESCRIPTION (provided by applicant): Human topoisomerase I (topo I) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. has successfully… More

Anti-Cancer Drug Design Targeting Human Topoisomerase I

Award Year / Program / Phase: 2001 / SBIR / Phase II
Agency: HHS
Principal Investigator: Lance J. Stewart
Award Amount: $748,938.00
Abstract:
DESCRIPTION (provided by applicant): Human topoisomerase I (topo I) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. has successfully… More

Crystallization Tools for Structural Genomics

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Hidong Kim
Award Amount: $0.00
Abstract:
DESCCRIPTION: Applicant?s abstract) An integrated, automated protein crystallization system,RoboHTC (Robotic High-Throughput Crystallization), will be developed, consisting of software and hardware tools suitable for large-scale protein crystallography projects, such as structural genomics. These… More

AUTOMATED PROTEIN CRYSTAL GROWTH IN LIPIDIC CUBIC PHASE

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Peter Nollert
Award Amount: $138,961.00
Abstract:
Information derived from the three-dimensional structure of proteins has been of increasing importance in the development of pharmaceuticals. Structures determined using 3-D X-ray crystallography have been vital in the development of anti-AIDS and anti-cancer agents. Membrane proteins constitute a… More

Fragment based inhibitor discovery of the MEP pathway in infectious organisms.

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bart L. Staker – 206-780-8912
Award Amount: $99,974.00
Abstract:
DESCRIPTION (provided by applicant): We will apply nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography to study enzymes from the methyl erythritol isoprenoid (MEP) biosynthetic pathway, which is essential in multiple pathogens and absent in humans. Identification and biophysical… More