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Rapid Detection Nano-Sensors for Biological Warfare Agents in Buildings and…

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
77106
Program Year/Program:
2006 / STTR
Agency Tracking Number:
A064-026-0064
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
EPIR Technologies Inc
590 Territorial Drive, Suite B Bolingbrook, IL -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2006
Title: Rapid Detection Nano-Sensors for Biological Warfare Agents in Buildings and HVAC Systems
Agency / Branch: DOD / ARMY
Contract: W9132T-06-C-0032
Award Amount: $99,961.00
 

Abstract:

Currently there is no real-time technology to detect airborne biological warfare agents (BWAs). Conventional technologies require 30 minutes to 1 hour. We propose to design, fabricate and test user-friendly, low-logistical-load biosensors capable of the real-time (~ 30 s. or less) detection and identification of airborne BWAs with high sensitivity and specificity for all classes of bioagents - bacterial spores, viruses, vegetative bacteria, and bacterial toxins - and many chemical agents. The biosensors developed will be easily used within building infrastructures, in particular HVAC systems. They will be user-friendly, have low-logistical-loads (i.e., reagents and consumables), and will allow the quantification of the density of airborne BWAs. They will allow automated remote response and the automated refreshing of antibodies and filters. They will utilize standard biofluidic techniques augmented with quantum-dot technology and optoelectronic techniques. They will incorporate two, or possibly three, different techniques for the detection and identification of BWAs: (1) the localization of antigens on grids having different pore sizes, (2) the tagging of these antigens with antibody-QD complexes and the observation of photoluminescence from the QDs bound to the localized antigens, and (3) for chemical agents and possibly small antigens, observing FRET between QDs and dies bound to the same antigen.

Principal Investigator:

James Garland
6307710203
jgarland@epir.com

Business Contact:

Sivalingam Sivananthan
President
6307710201
ssivananthan@epir.com
Small Business Information at Submission:

EPIR TECHNOLOGIES, INC.
590 Territorial Drive, Suite B Bolingbrook, IL 60440

EIN/Tax ID: 364196918
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
UNIV. OF ILLINOIS AT CHICAGO
Science and Engineering Offic
Chicago, IL 60607
Contact: Michael Stroscio
Contact Phone: (312) 413-5968
RI Type: Nonprofit college or university