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STTR Phase II:Engineering Clostridial Fermentation for Biobutanol Production

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
88528
Program Year/Program:
2010 / STTR
Agency Tracking Number:
0810568
Solicitation Year:
N/A
Solicitation Topic Code:
BE3
Solicitation Number:
N/A
Small Business Information
Bioprocessing Innovative C
4734 Bridal Path Court Dublin, OH 43017-2599
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2010
Title: STTR Phase II:Engineering Clostridial Fermentation for Biobutanol Production
Agency: NSF
Contract: 1026648
Award Amount: $500,000.00
 

Abstract:

This STTR Phase II project will develop novel engineered Clostridia strains for fermentation and economically produce butanol as a biofuel from sugars derived from starchy and lignocellulosic biomass. The conventional acetone-butanol-ethanol (ABE) fermentation has low butanol yield (<25%), butanol concentration (<16 g/L), and reactor productivity (<0.5 g/L?h) due to a strong butanol inhibition, and the fermentation process is difficult to improve due to the complicated metabolic pathways and gene regulation involved in the production microorganisms, mainly Clostridium acetobutylicum. The broader impact/commercial potential of the project is to produce butanol as a biofuel from sugars derived from starchy and lignocellulosic biomass. Biobutanol has great value as an alternative transportation fuel. There is a huge potential commercial and societal impact in improving yields and reducing costs of butanol production. The research and other activity proposed could lead directly to a marketable product and process and leads to several enabling technologies, including better manipulation of C. tyrobutylicum, further demonstration of strain improvements using the FBB, and others.

Principal Investigator:

I-Ching Tang
6147611552
bictang@sbcglobal.net

Business Contact:

I-Ching Tang
6147611552
bictang@sbcglobal.net
Small Business Information at Submission:

Bioprocessing Innovative C
4734 Bridal Path Court Dublin, OH 43017

EIN/Tax ID: 311501387
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
Ohio State University Research Foundation -DO NOT USE
1960 Kenny Rd
Columbus, OH 43210
Contact: Shang-Tian Yang
Contact Phone: 6142926611