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THEIR POTENTIAL APPLICATIONS TO A SUBUNIT VACCINE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
4793
Program Year/Program:
1986 / SBIR
Agency Tracking Number:
4793
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
NEUGENESIS CORPORATION
NEUGENESIS CORPORATION 871 INDUSTRIAL RD, STE J SAN CARLOS, CA 94070
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1986
Title: THEIR POTENTIAL APPLICATIONS TO A SUBUNIT VACCINE
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

HUMAN T-CELL LYMPHOTROPHIC VIRUS TYPE I (HTLV-I) IS THE CAUSATIVE AGENT OF AN AGGRESSIVE FORM OF T-CELL LEUKEMIA ENDEMIC TO CERTAIN GEOGRAPHIC AREAS BUT ALSO CURRENTLY INCREASING IN FREQUENCY IN THE SAME POPULATION AT RISK FOR DEVELOPING AIDS. SERO-EPIDEMIOLOGIC DATA SUGGEST THE PRESENCE OF A TYPE-COMMON NEUTRALIZATION DETERMINANT. THIS PROPOSAL SEEKS TO IDENTIFY AND PRODUCE, BY USE OF A RECOMBINANT DNA EXPRESSION SYSTEM, HTLV-I ENCODED EPITOPES TO ASSESS THEIR EFFECT ON IN VITRO MEASURES OF INFECTIVITY AND VIRUS NEUTRALIZATION. IMMUNOREACTIVE EPITOPES CHARACTERIZED IN THIS MANNER HAVE POTENTIAL APPLICATION TO EVENTUAL PRODUCTION OF AN HTLV-I SUBUNIT VACCINE.

Principal Investigator:

Gregory r reyes
PRINCIPAL INVESTIGATOR
4155941600

Business Contact:

Small Business Information at Submission:

Gene Labs Inc
871 Industrial Road Building J San Carlos, CA 94070

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No