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DIPAIN-Based Handheld Assay for the Detection of T-2 Toxin in Water Using a…

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
94909
Program Year/Program:
2010 / STTR
Agency Tracking Number:
A10A-021-0354
Solicitation Year:
N/A
Solicitation Topic Code:
ARMY 10T021
Solicitation Number:
N/A
Small Business Information
ANP TECHNOLOGIES, INC.
824 Interchange Boulevard Newark, DE 19711 9711
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2010
Title: DIPAIN-Based Handheld Assay for the Detection of T-2 Toxin in Water Using a Handheld Reader
Agency / Branch: DOD / ARMY
Contract: W911SR-10-C-0062
Award Amount: $99,939.00
 

Abstract:

A rapid assay for the detection of T2 trichothecene mycotoxin in water is proposed that will use ANP Technology, Inc.'s established handheld reader and rapid acetylcholinesterase (AChE) inhibitor test ticket format. Dipain-II and other candidate Dipain derivatives will be immobilized on cellulose and other solid supports mounted as discs in wells on the existing test ticket, similar to the AChE inhibitor ticket which uses a cellulose support for an enzyme substrate. The fluorescent signal emitted when the association complex of Dipain-II and T2 is formed can be measured by ANP's handheld reader by changing the light source to an LED at or near 366 nm output. The current camera onboard can measure the resultant yellow orange emission. A time to result of ~10 seconds with a sensitivity to as low as 50 ng/mL is expected. The ticket will use a built in comparator so that it is self-calibrating.

Principal Investigator:

Yli Remo Vallejo
VP of R&D
3022831730
yli@anptinc.com

Business Contact:

Robert Daniel
Sr. VP of Government Contracts
3022831730
robert@anptinc.com
Small Business Information at Submission:

ANP Technologies, Inc.
824 Interchange Boulevard Newark, DE 19711

EIN/Tax ID: 450478628
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
University of California, Irvine
Department of Chemistry
1102 Natural Sciences 2
Irvine, CA 92697
Contact: Zhibin Guan
Contact Phone: 9498245172