USA flag logo/image

An Official Website of the United States Government

Company Information:

Company Name: GENERAL BIOTECHNOLOGY, LLC
City: INDIANAPOLIS
State: IN
Zip+4: 46202-
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,080,383.00 11
SBIR Phase II $3,363,080.00 4

Award List:

Development of an Improved System for Platelet Storage

Award Year / Program / Phase: 1998 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: John K. Critser
Award Amount: $99,991.00
Abstract:
Survival rates of human platelets cryopreserved using current methods are very low (10%). This is largely due to a lack of knowledge regarding the fundamental cryobiology of this cell type. Because of this limitation, most blood banks maintain platelets in non-frozen solutions. Using this… More

EXPANSION OF PANCREATIC ISLETS USING NOVEL BIOMATERIAL

Award Year / Program / Phase: 1999 / SBIR / Phase I
Agency: HHS
Principal Investigator: John K. Critser
Award Amount: $99,997.00
Abstract:
Not Available A program is proposed to demonstrates a low cost material, design and manufacturing method for the elastomer-encapsulated, laterally-confined ceramic armor component to limit lateral damage, to increase ballistic efficiency, and to allow multiple impacts without ballistic performance… More

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $99,104.00
Abstract:
Not Available This proposal explores a variation of the Laser Induced Incandescence (LII) technique, and its integration with a multi-wavelength laser scattering/extinction technique, for measuring the soot concentration, soot primary size, and soot size distribution i

EXPANSION OF PANCREATIC ISLETS USING A NOVEL BIOMATERIAL

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: John K. Critser
Award Amount: $0.00

EXPANSION OF PANCREATIC ISLETS USING A NOVEL BIOMATERIAL

Award Year / Program / Phase: 2001 / SBIR / Phase II
Agency: HHS
Principal Investigator: John K. Critser
Award Amount: $388,521.00

A NOVEL FROZEN STORAGE SYSTEM FOR CORD BLOOD STEM CELLS

Award Year / Program / Phase: 2003 / SBIR / Phase II
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $1,000,407.00
Abstract:
DESCRIPTION (provided by applicant): With increasing effort directed toward purification and/or in vitro expansion of hematopoietic progenitor cells (HPCs) for either fundamental research or clinical applications, there is an associated, increased need for the development of improved, efficient… More

A NOVEL FROZEN STORAGE SYSTEM FOR CORD BLOOD STEM CELLS

Award Year / Program / Phase: 2003 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $0.00
Abstract:
DESCRIPTION (provided by applicant): With increasing effort directed toward purification and/or in vitro expansion of hematopoietic progenitor cells (HPCs) for either fundamental research or clinical applications, there is an associated, increased need for the development of improved, efficient… More

NOVEL SELF-NUCLEATING CRYOSTROGE DEVICES

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $107,508.00
Abstract:
DESCRIPTION (provided by applicant): The present proposal relates to a method of inducing ice formation (e.g. ice nucleation or "seeding") in aqueous solutions surrounding cells and tissues during low temperature preservation (cryopreservation). Typically, seeding is performed by touching the sample… More

AUTOMATED CLOSED SYSTEM FOR DMSO REMOVAL FROM PERIPHERAL BLOOD STEM CELLS

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $133,734.00
Abstract:
DESCRIPTION (provided by applicant): High dose chemotherapy followed by peripheral blood hematopoietic stem cell (PBSC) transplantation is frequently used for treating various hematologic malignancies. To facilitate this process, autologous PBSC are typically collected, cryopreserved and stored for… More

AUTOMATED CLOSED SYSTEM FOR DMSO REMOVAL FROM PERIPHERAL BLOOD STEM CELLS

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $1,003,794.00
Abstract:
DESCRIPTION (provided by applicant): High dose chemotherapy followed by peripheral blood hematopoietic stem cell (PBSC) transplantation is frequently used for treating various hematologic malignancies. To facilitate this process, autologous PBSC are typica lly collected, cryopreserved and stored for… More

Dental Pulp Derived Stem Cells: Optimizing Collection and Cryopreservation

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $106,064.00
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this application is to develop an understanding of the collection, processing and cryobiological characteristics of stem/progenitor cells recovered from extracted teeth with the ultimate culmination of these data to allow for a cryobank of… More

A Novel Device Design for Sperm Cryopreservation

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $137,261.00
Abstract:
DESCRIPTION (provided by applicant): Genetically engineered mouse (GEM) and rat (GER) lines are excellent animal models for many important human diseases (Cox, 2003; Green and Hudson, 2005). However, maintenance of these lines by standard breeding techniqu es is producing unsustainable pressure on… More

A NOVEL APPROACH TO GMP PRODUCTION, CRYOPRESERVATION AND DISTRIBUTION OF TOOTH DE

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $970,358.00
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this proposal is to build on our understanding of the collection, processing and cryobiological characteristics of stem/progenitor cells recovered from extracted teeth with the ultimate culmination of these data to develop a cryobank of… More

Therapeutic Angiogenesis by Universal Donor Endometrial Regenerative Cells

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods
Award Amount: $142,441.00
Abstract:
DESCRIPTION (provided by applicant): Therapeutic Angiogenesis by Universal Donor Endometrial Regenerative Cells (ERC) Abstract The proposed study seeks to develop a practical, off the shelf, universal donor, cell therapy for an advanced form of peripheral artery disease termed critical limb… More

A Novel, Inexpensive Cryopreservation System for Stable -80 degree C Storage of A

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Woods – 317-917-3450
Award Amount: $154,283.00
Abstract:
DESCRIPTION (provided by applicant): The overall goal of this proposal is to design and develop a type of cryopreservation media and an easy-to-use cooling device that allow the long-term storage and safe shipment of animal model germplasm (embryos and spermatozoa) and embryonic stem cells (ESCs) at… More