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THE LONG-TERM OBJECTIVE OF THIS WORK IS TO DEVELOP A RAPID, COLORIMETRIC,…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
3344
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
3344
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
GENESIS LABORATORIES, INC
10122 NE FRONTAGE RD Wellington, CO 80549 1703
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: THE LONG-TERM OBJECTIVE OF THIS WORK IS TO DEVELOP A RAPID, COLORIMETRIC, NON-INSTRUMENT-DEPENDENT ASSAY FOR PSYCHOACTIVE MARIJUANA CONSTITUENTS, NOTABLY 9-TETRAHYDROCANNIBINOL.
Agency: HHS
Contract: N/A
Award Amount: $46,975.00
 

Abstract:

THE LONG-TERM OBJECTIVE OF THIS WORK IS TO DEVELOP A RAPID, COLORIMETRIC, NON-INSTRUMENT-DEPENDENT ASSAY FOR PSYCHOACTIVE MARIJUANA CONSTITUENTS, NOTABLY 9-TETRAHYDROCANNIBINOL. GENESIS LABS' ""IMMUNOSTRIP'' ASSAY (PROTECTED BY PATENT) IS CONSTRUCTED IN A CONFIGURATION THAT IS APPLICABLE FOR THE RAPID DETECTION OF DRUGS AND METABOLITES IN BIOLOGICAL FLUIDS (E.G., URINE, BLOOD OR SALIVA). THE RELATIVE SIMPLICITY OF THE METHOD SUGGESTS ITS EASY USE BY MEDICALLY UNSOPHISTICATED INDIVIDUALS. WE WILL ATTEMPT INITIALLY TO DETERMINE TOTAL THC METABOLITES IN URINE AT A LEVEL OF 10100NG/ML. ULTIMATELY, OUR AIM IS TO INCREASE THE SENSITIVITY OF THE ASSAY SYSTEM INTO THE 110NG/ML RANGE. THIS WILL REQUIRE THE USE OF A HAND-HELD REFLECTOMETER ($1000 PER UNIT CURRENTLY) FOR READING THE STRIPS; HOWEVER, IT IS FEASIBLE. BY VARYING THE AMOUNT OF ANTIGEN AND ENZYME-MODIFIED ANTI-THC ANTIBODY WITHIN THE IMMUNOSTRIP WE CAN PRODUCE A VISUAL ASSAY WITHIN THIS LOWER RANGE. THE ASSAY HAS MANY APPLICATIONS FOR MONITORING DRUGS OF ABUSE, INCLUDING THC, AND THEREFORE WILL HAVE A MAJOR IMPACT ON OUR KNOWLEDGE OF THE HEALTH BENEFIT/RISK RATIO WITHIN POPULATIONS OF OUR SOCIETY WHO ABUSE OR REQUIRE DRUGS. BASED ON OUR ABILITY TO MONITOR OTHER HORMONES, DRUGS, AND SMALL HAPTENS USING THIS ASSAY, WE FEEL CONFIDENT THAT IN THE FUTURE BY USING HIGHLY SPECIFIC POLYCLONAL ANTISERA OR, MORE LIKELY, MONOCLONAL ANTIBODIES, IT MAY BE POSSIBLE TO MONITOR THC AND INDIVIDUAL METABOLITES IN BLOOD OR SALIVA WHICH MIGHT REFLECT RECENT CONSUMPTION OR CHRONIC ABUSE OF THC.

Principal Investigator:

Alan r. day
PRINCIPAL INVESTIGATOR
6128353446

Business Contact:

Small Business Information at Submission:

Genesis Labs, Inc.
5245 Edina Industrial Boulevar D Edina, MN 55435

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No