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Company Information:

Name: Genex Corpon
Address: 16020 Industrial Dr
Gaithersburg, MD 20877
Located in HUBZone: No
Woman-Owned: No
Minority-Owned: No
URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $630,000.00 13
SBIR Phase II $980,000.00 2

Award List:

NUCLEASE A IN BACILLUS SUBTILIS INTERACTIVE EXPERT EDITING SUBSYSTEM LOW-COST HRPT DIRECT READOUT STATION

Award Year / Program / Phase: 1986 / SBIR / Phase I
Agency: DOC
Principal Investigator:
Award Amount: $30,000.00
Abstract:
Bovine pancreatic ribonuclease a (rnase a) is a model systemfor establishing rules that govern protein stability and folding. by learning and applying these rules, more robust enzymes of various types could be designed for commercial applications. synthesis, cloning and expression in… More

L-ASPARAGINASE IS AN IMPORTANT ADDITION TO COMBINATION CHEMOTHERAPY PROTOCOLS FOR CHILDHOOD ACUTE LYMPHOCYTIC LEUKEMIA.

Award Year / Program / Phase: 1986 / SBIR / Phase I
Agency: HHS
Principal Investigator: David m anderson , PRINCIPAL INVESTIGATOR
Award Amount: $50,000.00
Abstract:
L-asparaginase is an important addition to combination chemotherapy protocols for childhood acute lymphocytic leukemia. however, immunological reactions to this foreign protein can greatly limit its therapeutic effectiveness. therefore, the production of non-cross reacting l- asparaginase variants… More

MICROBIAL PRODUCTION OF PROTEIN ADHESIVE

Award Year / Program / Phase: 1986 / SBIR / Phase I
Agency: HHS
Principal Investigator: David M Anderson , Principal Investigator
Award Amount: $50,000.00

BACILLUS HOSTS FOR PHARMACEUTICAL PROTEIN SECRETION

Award Year / Program / Phase: 1987 / SBIR / Phase I
Agency: HHS
Principal Investigator: Stephen r fahnestock phd
Award Amount: $50,000.00
Abstract:
Bacillus subtilis is an advantageous host organism for the production of foreign proteins at low cost because it has the capacity to secrete high levels of proteins into the growth medium. several proteins of bacterial origin encodedby plasmid-borne recombinant genes have been secreted by b.… More

MICROBIAL PRODUCTION OF PROTEIN ADHESIVE

Award Year / Program / Phase: 1988 / SBIR / Phase II
Agency: HHS
Principal Investigator: David M Anderson , Principal Investigator
Award Amount: $480,000.00
Abstract:
The objectiive of this phase i research is to develop an efficient microbial process for commercial production of a polyphenolic protein adhesive similar to that produced by the mussel mytilis edulis. unlike most adhesives, this strong adhesive can set and adhere to surfaces in wet environments.… More

IMPROVED SECRETION OF HUMAN SERUM ALBUMIN IN BACILLUS

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
Gene fusions have been constructed that promote the efficient secretion of human serum albumin (hsa) from bacillus subtilis. hsa-encoding sequences are fused to promoter and secretion signal-encoding sequences derived from b. amyloliquefaciens alpha-amylase (amy) and neutral protease (npr) genes.… More

A SINGLE-CHAIN ANTIGEN-BINDING PROTEIN THAT BINDS CEA

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00
Abstract:
Genex scientists have developed proprietary technology for the design of genes which code for the variable regions of antibody molecules linked by polypeptide linkers. the genescode for both v(l) and v(h) regions and the resulting protein is synthesized as a single polypeptide chain in e. coli.… More

ANTI-FLUORESCEIN SINGLE-CHAIN ANTIGEN-BINDING PROTEIN

Award Year / Program / Phase: 1988 / SBIR / Phase I
Agency: HHS
Principal Investigator:
Award Amount: $50,000.00

ANTI-FLUORESCEIN SINGLE-CHAIN ANTIGEN-BINDING PROTEIN

Award Year / Program / Phase: 1989 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $500,000.00
Abstract:
Using its proprietary protein engineering technology genex has designed and produced a novel antigen-binding protein. the dna sequences for the heavy (h) and light (l) chains of a monoclonal antibody to bovine growth hormone (bgh) havebeen cloned at genex and modified to encode the antigen-binding… More

AFFINITY BIOADHESIVES ENGINEERED FOR CELL CULTURE APPLICATIONS

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: NSF
Principal Investigator: Dr Rebecca P Link , Principal Research Scientist
Award Amount: $50,000.00
Abstract:
The objective of this research program is to develop throughgenetic engineering technology a family of "affinity bioadhesives" for specific eucaryotic cell attachment applications. in an ongoing research program, genex has produced a series of recombinant adhesive proteins based on the polyphenolic… More

"BIOSYNTHESIS OF A PROTEIN WHICH BINDS TO MURINE IGM IMMUNOGLOBIN"

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: NSF
Principal Investigator: Robert E Bird , Director
Award Amount: $50,000.00
Abstract:
The objective of this proposed program is to develop an affinity protein that is specific for murine igm. the approach for achieving this objective is to produce a single-chain antibody (sca) protein with specificity for mouse igm. the sca protein will be designed from the variable regions of the… More

CRYSTALLOGRAPHIC AREA DETECTOR SOFTWARE

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: NSF
Principal Investigator: Dr Andrew J Howard
Award Amount: $50,000.00
Abstract:
We propose to develop a software package for the processing of macromolecular diffraction data from electronic position-sensitive area detectors, with particular application to data from high-flux storage ring x-ray sources. existing packages of software are either geared toward data from… More

SYNTHESIS OF A SCA PROTEIN WITH ENZYMATIC ACTIVITY

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: Leslie S Johnson
Award Amount: $50,000.00
Abstract:
A single-chain antibody (sca) protein with catalytic activity will be prepared. the sca protein will be designedfrom the variable region dequences of one of two antibodies found to have lipase activity, either 2h6 or 21h3. a gene to synthesize this protein will be constructed, and the protein will… More

ENGINEERING OF NEW BINDING SPECIFICITIES OF PROTEIN A

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: David R Filpula
Award Amount: $50,000.00
Abstract:
The objective of this research is to use protein engineering to generate staphylococcal protein a variants that possess strong binding affinity for immunoglobulin species that are not significantly bound by natural protein a. the experimental program will involve a sequential series of experiments… More

SYNTHESIS OF SCA PROTEIN WITH HUMAN IGM SPECIFICITY

Award Year / Program / Phase: 1990 / SBIR / Phase I
Agency: HHS
Principal Investigator: Robert E Bird
Award Amount: $50,000.00
Abstract:
A single-chain antibody (sca) protein with specificity for human igm will be prepared. the sca protein will be designed from the variable regions of the antihuman igm monoclonal antibody, da4.4. a gene to synthesize this protein will be constructed, and the protein will be expressed in escherichia… More