Not Available Rhenium has been demonstrated to be the ideal material for construction of structures exposed to high temperature propellant exhausts, including divert systems, rocket motor throats, and gun tubes. Unfortunately, rhenium has three drawbacks, consisting of high cost, poor… More

The human genome project spurred the development of high throughput technologies, especially in the area of DNA sequencing. Not only has this effort produced a draft of the human genome, it's catalyzed development of an entire industry based on DNA sequencing and genomics. Since… More

The human genome project spurred the development of high throughput technologies, especially in the area of DNA sequencing. Not only has this effort produced a draft of the human genome, it's catalyzed development of an entire industry based on DNA sequencing and genomics. Since… More

DESCRIPTION (provided by applicant): Optical mapping is a method by which large-scale, efficient restriction digests can be utilized as an alternative to sequence assembly. In traditional sequence assembly, a genetic target is fragmented, amplified, and sequenced. Software algorithms then find… More

DESCRIPTION (provided by applicant): Geospiza Inc. and the National Center for Supercomputing Applications (NCSA) are creating a standards based software framework around NCSA's Heirarchical Data Format (HDF5). The envisioned framework will integrate algorithms important in DNA and protein sequence… More

DESCRIPTION (provided by applicant): Seeing is Believing: Turning Abstract Polymorphisms Into Concrete Structures Project Summary If the U.S. is to remain competitive in a global market, continue to interest young people in careers in science and medicine, and help the general public see health… More

DESCRIPTION (provided by applicant): In November 2008, The Scientist opened an on-line opinion piece with the following quote: After tens of billions of US federal dollars (plus billions more from private sources) and nearly 40 years of aggressive resear ch, the war on cancer is depressingly far… More

DESCRIPTION (provided by applicant): The first wave of Next Generation ( Next Gen ) sequencing technologies combines molecular resolution with extremely high throughput to dramatically reduce sequencing costs and increase assay sensitivity and specificity. These technologies will provide large… More

DESCRIPTION (provided by applicant): Next generation DNA sequencing (NGS) technologies hold great promise as tools for building a new understanding of health and disease. In the case of understanding cancer, deep sequencing provides more sensitive ways todetect the germline and somatic mutations… More