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MODIFICATION OF CARBON FOR WEARABLE ARTIFICIAL KIDNEYS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7224
Program Year/Program:
1987 / SBIR
Agency Tracking Number:
7224
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Giner, Inc.
89 Rumford Avenue Newton, MA 02466-1311
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1987
Title: MODIFICATION OF CARBON FOR WEARABLE ARTIFICIAL KIDNEYS
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THE LONG-TERM OBJECTIVE OF THE PROPOSED WORK IS TO MODIFY CARBON CARTRIDGES FOR EFFICIENT REMOVAL OF BLOOD TOXINS. CARBON ADSORPTION IS EMPLOYED FOR THE REMOVAL OF STRONGLY ADSORBABLE TOXINS IN SOME ARTIFICIAL KIDNEY SYSTEMS AS WELL AS IN MOST ARTIFICIAL LIVER CONFIGURATIONS. IN THE REGENERATIVE ARTIFICIAL KIDNEY APPLICATION, A CARBON BED WITH ABOUT 250 GRAMS OF ACTIVATED CARBON IS USED TO ADSORB THE STRONGLY ADSORBABLE SPECIES THAT ACCUMULATE BETWEEN DIALYSIS SESSIONS. THE SPECIFIC AIM OF PHASE I IS TO DEMONSTRATE THE FEASIBILITY OF RELIABLE MODIFICATION OF A CARBON BED. THE MODEL SPECIES TO BE INVESTIGATED WILL BE CREATININE, URIC ACID AND VITAMIN B12, AND UREA. WITH THE SUCCESSFUL COMPLETION OF THESE MODIFICATION METHODS, GINER, INC. WILL PREPARE A PRELIMINARY CONCEPTUAL DESIGN OF A REGENERATION SYSTEM AND A PROCEDURE FOR TWO APPLICATIONS: (1) CARBON BEDS USED TO ADSORB URIC ACID, CREATININE MIDDLE MOLECULES, ETC., IN REGENERATIVE, CLOSED-LOOP ARTIFICAL KIDNEYS, SUCH AS THE ELECTROCHEMICALLYREGENERATIVE ARTIFICIAL KIDNEY BEING DEVELOPED BY GINER, INC. AND THE REDY SYSTEM, AND (2) AN ARTIFICIAL KIDNEY BASEDON THE ADSORPTION OF UREA USING CARBON.

Principal Investigator:

Jose d giner phd
6178997270

Business Contact:

Small Business Information at Submission:

Giner Inc
14 Spring Street Waltham, MA 02254

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No