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DIAMOND COATED HEART VALVES

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
16735
Program Year/Program:
1991 / SBIR
Agency Tracking Number:
16735
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Giner, Inc.
89 Rumford Avenue Newton, MA 02466-1311
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1991
Title: DIAMOND COATED HEART VALVES
Agency: HHS
Contract: N/A
Award Amount: $49,995.00
 

Abstract:

HEART VALVES MADE FROM PYROLYTIC CARBON HAVE BEEN USED CLINICALLY FOR OVER 20 YEARS WITH BILEAFLET, CENTRAL-FLOW DESIGNS DOMINATING THIS MARKET; HOWEVER, AN INCREASED NUMBER OF CLINICALLY SIGNIFICANT POSTOPERATIVE BLEEDING EPISODES HAVE BEEN DOCUMENTED FOR PATIENTS WITH MECHANICAL VALVES. THE LONG- TERM OBJECTIVE IS TO IMPROVE PRESENT-DAY CENTRAL FLOW/BILEAFLET PYROLYTIC CARBON VALVES AND TO ACCOMPLISH THESE IMPROVEMENTS WITH ABSOLUTELY MINIMAL CHANGES IN THE MATERIAL AND NO CHANGES IN VALVE DESIGN. WE WILL ACHIEVE THIS GOAL BY COATING THE PYROLYTIC CARBON VALVES WITH CVD DIAMOND FILMS. THE SPECIFIC AIMS FOR PHASE I ARE: 1) DEMONSTRATION THAT CVD DIAMOND COATINGS CAN BE RELIABLY DEPOSITED ON THE PYROLYTIC CARBON SURFACE OF HEART VALVE PARTS AND PRODUCTION OF SUFFICIENT NUMBERS OF COATED PARTS FOR TESTING; 2) CHARACTERIZATION OF THE DEPOSITED FILMS FOR (A) UNIFORMITY OF DEPOSITION, SURFACE MORPHOLOGY AND THICKNESS, (B) PHASE PURITY AND MICROSTRUCTURAL CHARACTERIZATION, AND (C) ADHESION OF THE DIAMOND FILM TO THE SUBSTRATE, AND 3) CHARACTERIZATION OF THE CHEMICAL RESISTANCE AND INTEGRITY OF THE COATINGS. DEMONSTRATION OF IMPROVEMENTS IN BIOCOMPATIBILITY AND CAVITATION RESISTANCE IS PLANNED FOR PHASE II.

Principal Investigator:

Sarangapani, S
Principal Investigator
6178997270

Business Contact:

1 r43 hl47238-01
Small Business Information at Submission:

Giner, Inc
14 Spring Street Waltham, MA 02154

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No