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Company Information:

Company Name: BIOSENTINEL, LLC
City: Madison
State: WI
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $949,846.00 3
SBIR Phase II $1,842,045.00 2

Award List:

A Cell-based Assay for Botulinum Neurotoxin Detection and Development

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ward C. Tucker
Award Amount: $587,536.00
Abstract:
DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNT) are the most toxic substances known to humans causing respiratory failure upon poisoning. BoNT's lethality and ease of production has led to a category A bioterrorism agent designation for BoNT by the Department of Defense (DoD).… More

SBIR Phase I:De novo assays for detection of the proteolytic activity in botulinum neurotoxin-based pharmaceuticals

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: NSF
Principal Investigator: Ward Tucker, DPhil
Award Amount: $150,000.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project proposes to develop a universal, in vitro assay for determining the enzymatic activity of botulinum neurotoxin (BoNT)-based pharmaceuticals. BoNTs are used in many cosmetic and pharmaceutical applications due to their long lasting… More

A Cell-based Assay for Botulinum Neurotoxin Detection and Development

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: Ward C. Tucker – 608-441-8172
Award Amount: $1,425,680.00
Abstract:
DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNTs) are the most toxic substances known to humans, causing respiratory failure. Because of their lethality and ease of production, the Department of Defense (DoD) designates BoNTs as a categoryA bioterrorism agent. Developing effective,… More

Validation of a cell-based assay for BoNT/A detection against the mouse bioassay

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Ward C. Tucker – 608-441-8172
Award Amount: $212,310.00
Abstract:
DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNT) are the most toxic substances known to humans, causing respiratory failure upon intoxication. Despite their lethality, BoNTs have clinical health and cosmetic applications and are currentlyFDA-approved for treating cervical dystonia,… More

SBIR Phase II: De novo assays for detection of the proteolytic activity in botulinum neurotoxin-based pharmaceuticals

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: NSF
Principal Investigator: Ward Tucker
Award Amount: $416,365.00
Abstract:
This Small Business Innovation Research (SBIR) Phase II project proposes to complete development of a universal, in vitro assay for determining the enzymatic activity of botulinum neurotoxin (BoNT)-based pharmaceuticals. This assay, called BoTest Matrix A Assay, will enable standardized comparisons… More