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BISPECIFIC ANTIBODY FOR DIRECTED DELIVERY OF TAXOL

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
19070
Program Year/Program:
1992 / SBIR
Agency Tracking Number:
19070
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
HAWAII BIOTECH, INC.
99-193 AIEA HEIGHTS DRIVE, SUITE 200 AIEA, HI -
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1992
Title: BISPECIFIC ANTIBODY FOR DIRECTED DELIVERY OF TAXOL
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

WE WILL ACHIEVE THE SELECTIVE DELIVERY OF CYTOTOXIC AGENTS THROUGH THE USE OF BISPECIFIC ANTIBODIES. TAXOL IS A PROMISING NEW ANTICANCER AGENT ISOLATED IN LOW YIELD FROM THE BARK OF THE PACIFIC YEW TREE, TAXUS BREVIFOLIA. THE APPLICANT WILL PREPARE A THIOETHER-LINKED BISPECIFIC ANTIBODY WITH DIAL SPECIFICITY FOR TAXOL AND HUMAN CANCER CELLS. IT IS ASSERTED THAT THIS BISPECIFIC ANTIBODY WILL POTENTIATE THE ACTION OF TAXOL IN TARGET TISSUE, MINIMIZE SIDE-EFFECTS, AND REDUCE THE TOTAL AMOUNT OF TAXOL REQUIRED FOR EFFECTIVE THERAPY.

Principal Investigator:

Gary S Bignami
8084865333

Business Contact:

Small Business Information at Submission:

Hawaii Biotechnology Group Inc
99-193 Aiea Heights Drive Aiea, HI 96701

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No