BISPECIFIC ANTIBODY FOR DIRECTED DELIVERY OF TAXOL

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 19070	Program Year/Program: 1992 / SBIR
Agency Tracking Number: 19070	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: HAWAII BIOTECH, INC.
99-193 AIEA HEIGHTS DRIVE, SUITE 200 AIEA, HI 96701-3900
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 1: Fiscal Year: 1992

Title: BISPECIFIC ANTIBODY FOR DIRECTED DELIVERY OF TAXOL

Agency: HHS

Contract: N/A

Award Amount: $50,000.00

Abstract:
WE WILL ACHIEVE THE SELECTIVE DELIVERY OF CYTOTOXIC AGENTS THROUGH THE USE OF BISPECIFIC ANTIBODIES. TAXOL IS A PROMISING NEW ANTICANCER AGENT ISOLATED IN LOW YIELD FROM THE BARK OF THE PACIFIC YEW TREE, TAXUS BREVIFOLIA. THE APPLICANT WILL PREPARE A THIOETHER-LINKED BISPECIFIC ANTIBODY WITH DIAL SPECIFICITY FOR TAXOL AND HUMAN CANCER CELLS. IT IS ASSERTED THAT THIS BISPECIFIC ANTIBODY WILL POTENTIATE THE ACTION OF TAXOL IN TARGET TISSUE, MINIMIZE SIDE-EFFECTS, AND REDUCE THE TOTAL AMOUNT OF TAXOL REQUIRED FOR EFFECTIVE THERAPY.

Principal Investigator:
Gary S Bignami
8084865333

Business Contact:

Small Business Information at Submission:

Hawaii Biotechnology Group Inc
99-193 Aiea Heights Drive Aiea, HI 96701

EIN/Tax ID:

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No