Synthesis of a Taxol-Cehalosporin Prodrug
A Taxol prodrug derivative will be prepared. This compound will be tested for its differential cytotoxicity compared to Taxol and for its ability to be enzymatically activated. The cytotoxicity of the prodrug in combination with a monoclonal-antibody enzyme conjugate in the presence of targeted and non-targeted cells will also be examined.
Small Business Information at Submission:
Principal Investigator:Sean O'Malley
Hawaii Biotechnology Group,
99-193 Aiea Heights Drive Aiea, HI 96701
Number of Employees: