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Company Information:
Name:
HELIX THERAPEUTICS, LLC
Address:
HELIX THERAPEUTICS, LLC
25 Science Park
New Haven, CT 06511
25 Science Park
New Haven, CT 06511
Located in HUBZone:
No
Woman-Owned:
No
Minority-Owned:
No
URL:
N/A
Phone:
N/A
Award Totals:
Award List:
Targeted CCR5 Gene Inactivation Using Peptide Nucleic Acids
Award Year / Program / Phase:
2008 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Award Amount:
$99,999.00
Abstract:
DESCRIPTION (provided by applicant): The proposed work is to develop a therapeutic gene targeting agent for the treatment of HIV disease. Our approach is to use triplex-forming oligonucleotides (TFOs) and peptide nucleic acids (PNAs), which bind to duplex
DNA in a sequence-specific manner. Initial… More
Beta-Globin Gene Correction Using Peptide Nucleic Acids for the Treatment of Sick
Award Year / Program / Phase:
2010 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Gerald F. Vovis
Award Amount:
$228,490.00
Abstract:
DESCRIPTION (provided by applicant): This is a proposal to test the feasibility of using triplex-forming oligonucleotides to correct the sickle cell disease (SCD) mutation in human CD34+ cells. SCD is one of the most common human genetic diseases and is th
e result of one specific inherited mutation… More