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THE MEASUREMENT OF GLYCOSYLATED HEMOGLOBIN IS PROBABLY THE BEST MEANS OF…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
1375
Program Year/Program:
1984 / SBIR
Agency Tracking Number:
1375
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Hybridoma Sciences Inc.
4761 High Howell Road Suite D Atlanta, GA 30084
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1984
Title: THE MEASUREMENT OF GLYCOSYLATED HEMOGLOBIN IS PROBABLY THE BEST MEANS OF ASSESSING GLUCOSE CONTROL OVER TIME IN DIABETICS.
Agency: HHS
Contract: N/A
Award Amount: $48,741.00
 

Abstract:

THE MEASUREMENT OF GLYCOSYLATED HEMOGLOBIN IS PROBABLY THE BEST MEANS OF ASSESSING GLUCOSE CONTROL OVER TIME IN DIABETICS. IT NOW APPEARS THERE IS INVERSE CORRELATION BETWEEN THE CONTROL OF GLUCOSE METABOLISM AND COMPLICATIONS OF THE DISEASE IN THAT WELL CONTROLLED DIABETICS DO MUCH BETTER. THE CURRENTLY AVAILABLE ASSAY SYSTEMS FOR QUANTITATING GLYCOSYLATED HEMOGLOBIN ARE BULKY, TIME CONSUMING AND EXPENSIVE AND THEREFORE ARE IDEAL CANDIDATES FOR REPLACEMENT WITH A MONOCLONAL ANTIBODY BASED IMMUNOASSAY. TO THAT END ANTIBODIES FROM HYBRIDOMA CLONES DERIVED FROM FUSIONS OF SPLEEN CELLS FROM MICE IMMUNIZED WITH THE GLYCOSYLATED HEMOGLOBIN ARE CURRENTLY BEING EVALUATED AND PLANS ARE TO DEVELOP ADDITIONAL HYBRIDOMAS AS PART OF PHASE I. DURING PHASE II A TWO-SITE IMMUNOMETRIC ASSAY WILL BE DEVELOPED FOR QUANTITATION OF GLYCOSYLATED HEMOGLOBIN FOR USE IN THE CLINICAL LABORATORY.

Principal Investigator:

Daniel b. cawley
RESEARCH SCIENTIST
0

Business Contact:

Small Business Information at Submission:

Hybridoma Sciences Inc.
4690 Hammermill Road Atlanta, GA 30084

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No