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ENHANCEMENT OF OSSEOINTEGRATION USING RESONANT EM FIELDS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
13792
Program Year/Program:
1990 / SBIR
Agency Tracking Number:
13792
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Iatromed Inc
4645 N 32nd St Phoenix, AZ 85018
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1990
Title: ENHANCEMENT OF OSSEOINTEGRATION USING RESONANT EM FIELDS
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

DURING THIS PERIOD 1983 TO 1987, THE NUMBER OF DENTAL IMPLANTS INSERTED IN THE UNITED STATES INCREASED 4-FOLD AND THE NUMBER OF PRACTITIONERS PERFORMING IMPLANTS INCREASED 10-FOLD. FURTHERMORE, IT IS ESTIMATED THAT 300,000 OR MORE DENTAL IMPLANTS WILL BE USED IN THE UNITED STATES BY 1992. OSSEOINTEGRATION, PARTICULARLY IN TWO-STAGE ROOT-FORM IMPLANTS, HAS BEEN SHOWN TO RESULT IN EXCELLENT PERFORMANCE OF DENTAL IMPLANTS. HOWEVER, ACHIEVING OSSEOINTEGRATION OFTEN REQUIRES EXTENSIVE PERIODS OF TIME (1 YEAR) WITH THE IMPLANT OUT OF FUNCTION. WITH EARLY FUNCTIONAL RESTORATION,OSSEOINTEGRATION IS OFTEN NEVER ACHIEVED. THE LONG-TERM OBJECTIVE OF THIS WORK IS TO DEVELOP A NONINVASIVE TREATMENT MODALITY THAT CAN BE USED TO ENHANCE OSSEOINTEGRATION BY EITHER REDUCING THE TIME TO ACHIEVE IT OR BY PROVIDING PREDICTABLE BONE AUGMENTATION. THE AIM OF THIS PHASE I STUDY IS TO DEMONSTRATE THE FEASIBILITY OF UTILIZING RESONANT ELECTROMAGNETIC FIELDS TO STIMULATE OSTEOGENESIS AND THEREBY ENHANCE DENTAL IMPLANT OSSEOINTEGRATION. USING A CANINE TRANSCORTICAL MODEL, ANIMALS WILL BE PLACED IN ALIGNED STATIC AND TIME-VARYING MAGNETIC FIELDS FOR PERIODS OF 3 AND 6 WEEKS. CONDITIONS ON THE FIELD WILL BE SET TO STIMULATE THE TRANSPORT ACROSS CELL MEMBRANES OF SPECIFIC IONS. THE OSSEOINTEGRATION POTENTIAL OF THE RESONANT ELECTROMAGNETIC FIELD TREATMENT WILL BE STUDIED, UTILIZING ATTACHMENT STRENGTH AND HISTOLOGY OF THE INTERFACEIN THE TREATED LIMBS AS COMPARED TO THE UNTREATED CONTROL LIMBS.

Principal Investigator:

Allan M Weinstein
6024682465

Business Contact:

Small Business Information at Submission:

Iatromed Inc
4645 N 32nd St Phoenix, AZ 85018

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No