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Development of a low-cost hardware accelerator for 3D image registration.

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
89500
Program Year/Program:
2008 / STTR
Agency Tracking Number:
CA137886
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
IGI TECHNOLOGIES, INC.
5904 MEADOW ROSE ELKRIDGE, MD -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: Development of a low-cost hardware accelerator for 3D image registration.
Agency: HHS
Contract: 1R41CA137886-01
Award Amount: $149,625.00
 

Abstract:

DESCRIPTION (provided by applicant): Our overall goal is to develop a novel computing solution for automatic and accurate registration (spatial alignment) of three-dimensional (3D) medical images of any modality and any anatomy (rigid or deformable) in 1 m inute. Such capability currently does not exist. Existing image registration solutions have limited accuracy and/or limited applicability, preventing wide and routine clinical use. Building on significant prior academic research, we will demonstrate the fe asibility of creating the proposed technology in this 1-year STTR Phase I project. After demonstrating feasibility, we will create a fully functional prototype a compact, relatively low- cost (manufacturing cost: ~ 20,000) PC board of hardware-accelerated image registration, with commercialization as the ultimate goal. Image registration is a fundamental need in modern medicine a need that remains unmet. It is the necessary first step before images with complementary information can be fused, or images take n at different times can be subtracted to quantify anatomic/physiologic changes. Image registration has numerous other applications, including the registration of pre- and intraoperative images in a host of emerging minimally invasive image-guided interven tions. Through system-level simulation and performance characterization (our 2 specific aims), we will create a software simulation of the proposed hardware accelerator in Phase I. We will register existing images of the brain, lungs, and abdomen using thi s functionally identical and similar-speed simulator to show accurate image registration in 1 min or less. Meeting these performance milestones will provide evidence that this clinically viable and multipurpose computing solution can be created and will ju stify transitioning to Phase II and continued funding. Our proposed low-cost, ultrafast, easy-to-use, and accurate computing solution promises to unlock the full potential of medical image registration. PROJECT HEALTH RELEVANCE: Combining 2 or more medical images of different types gives more precise information on a patient's condition. Comparing images taken at different times helps monitor how a disease is responding to treatment. In either case, image registration (alignment) is the crucial first step. Current image registration methods are slow, complex, and tedious, with limited practical applicability. We propose developing automatic, high-speed, three-dimensional registration capabilities that are applicable to most organs and image types. We will de monstrate the feasibility of creating such a technology in Phase I before its full development planned for Phase II.

Principal Investigator:

Business Contact:

Small Business Information at Submission:

IGI TECHNOLOGIES, INC.
IGI TECHNOLOGIES, INC. 5904 MEADOW ROSE ELKRIDGE, MD 21075

EIN/Tax ID: 161152343
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No