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THIS PROJECT IS CONCERNED WITH THE DEVELOPMENT OF NONENZYMATIC REAGENTS FOR…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
2984
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
2984
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
IMMUNOMEDICS, INC.
300 The American Road Morris Plains, NJ 07950-
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: THIS PROJECT IS CONCERNED WITH THE DEVELOPMENT OF NONENZYMATIC REAGENTS FOR IMMUNOHISTOCHEMISTRY, WITH EMPHASIS ON ADAPTING THE NEW TECHNOLOGY TO THE EXPANDING FIELD OF IMMUNOHISTOCHEMICAL DIAGNOSIS OF CANCER.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

THIS PROJECT IS CONCERNED WITH THE DEVELOPMENT OF NONENZYMATIC REAGENTS FOR IMMUNOHISTOCHEMISTRY, WITH EMPHASIS ON ADAPTING THE NEW TECHNOLOGY TO THE EXPANDING FIELD OF IMMUNOHISTOCHEMICAL DIAGNOSIS OF CANCER. PHASE I INVOLVES THE DEVELOPMENT OF THE FIRST FAMILY OF REAGENTS, NAMELY, PHENAZINE DERIVATIVES CONJUGATED TO ANTIBODIES AGAINST TUMOR-ASSOCIATED ANTIGENS, AND DETERMINATION OF STABILITY, IMMUNOREACTIVITY, AND STAINING OF TUMOR TISSUE SECTIONS. PHASE II WILL BE DEVOTED TO THE DEVELOPMENT OF STAINING PROTOCOLS AND KITS AND EXPLORATIONS OF NEW CLASSES OF STAINING REAGENTS, INCLUDING ARTIFICIAL ENZYMES AND IMPROVING THE CONJUGATION OF THESE LIGANDS TO THE ANTIBODIES (ESPECIALLY VIA BRIDGING SYNTHETIC POLYMERS). IT IS EXPECTED THAT THE NEW NONENZYMATIC REAGENTS WILL PROVE TO BE MORE STABLE THAN THE CONVENTIONAL ANTIBODY-ENZYME REAGENTS, THUS HAVING A LONGER SHELF LIFE, AND WILL BE

Principal Investigator:

Dan shochat
PRINCIPAL INVESTIGATOR
2014564779

Business Contact:

Small Business Information at Submission:

Immunomedics, Inc.
100 Bergen Street Newark, NJ 07103

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No