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Company Information:

Company Name: InBios International, Inc.
City: Seattle
State: WA
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: (206) 344-5821

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $3,835,128.00 20
SBIR Phase II $6,853,548.00 10
STTR Phase I $986,395.00 2

Award List:

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Syamal Raychaudhuri
Award Amount: $99,938.00

N/A

Award Year / Program / Phase: 2000 / SBIR / Phase I
Agency: HHS
Principal Investigator: Syamal Raychaudhuri
Award Amount: $98,994.00

New Generation Test for Visceral Leishmaniasis Diagnosis

Award Year / Program / Phase: 2001 / SBIR / Phase I
Agency: HHS
Principal Investigator: Syamal Raychaudhuri
Award Amount: $0.00
Abstract:
DESCRIPTION (provided by applicant): Visceral leishmaniasis (VL) is a disease with high mortality in both developed and developing countries. The causative agents are the parasites Leishmania chagasi, donovani and infantum depending on geographic location. In Mediterranean… More

New Generation Test for Visceral Leishmaniasis Diagnosis

Award Year / Program / Phase: 2001 / SBIR / Phase II
Agency: HHS
Principal Investigator: Syamal Raychaudhuri
Award Amount: $391,863.00
Abstract:
DESCRIPTION (provided by applicant): Visceral leishmaniasis (VL) is a disease with high mortality in both developed and developing countries. The causative agents are the parasites Leishmania chagasi, donovani and infantum depending on geographic location. In Mediterranean… More

A NOVEL, RAPID TEST FOR DIAGNOSIS OF T.CRUZI INFECTION

Award Year / Program / Phase: 2002 / SBIR / Phase I
Agency: HHS
Principal Investigator: Syamal Raychaudhuri
Award Amount: $99,812.00
Abstract:
DESCRIPTION (provided by applicant): This proposal is to produce a rapid serodiagnostic and accurate confirmatory test for detection of Trypanosoma cruzi infections built on a novel recombinant antigen. This parasite, transmitted via blood transfusion, is prevalent in Latin America, and the… More

Geographically robust rapid assay for T. cruzi infection

Award Year / Program / Phase: 2004 / SBIR / Phase II
Agency: HHS
Principal Investigator: Syamal X. Raychaudhuri
Award Amount: $849,601.00
Abstract:
DESCRIPTION (provided by applicant): This proposal is to develop a rapid serodiagnostic and accurate confirmatory test for detection of Trypanosoma cruzi infections built on a set of novel recombinant antigens. This parasite is transmitted via blood transfusion, is prevalent in Latin America, and is… More

Field Deployable Diagnostic Test for Active Cutaneous Leishmania and a Test for Latent Infection

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Raymond Houghton, Senior Scientist
Award Amount: $119,515.00
Abstract:
The proposed immunochromatographic diagnostic test would be a useful rapid diagnostic test for the direct detection of Leishmania parasites responsible for cutaneous leishmaniasis in soldiers exhibiting skin lesions. It would have application in detecting Leishmania parasites directly from needle… More

Development of rapid detection tests for B pseudomallei

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Raymond Houghton
Award Amount: $975,862.00
Abstract:
DESCRIPTION (provided by applicant): The Gram negative bacterium Burkholderia pseudomallei causes human melioidosis, a rapidly progressing and frequently fatal disease if not treated early. It is endemic in areas of NE Thailand, Southeast Asia and northern parts of Australia and is listed as a… More

Rapid Immunoassay for the Detection of the Bacterium Producing Necrotizing Hepatopancreatitis in Cultured Penaeid Shrimp

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: USDA
Principal Investigator: Raymond Houghton
Award Amount: $79,601.00
Abstract:
The rapid test developed here will provide for improved detection of NHP bacterial infections in the field. This in turn will have economic consequences by enabling shrimp farmers to more rapidly respond to and contain infections.

Development of a multiplexed point-of-care assay for the detection of infectious agents causing fever in deployed soldiers.

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency / Branch: DOD / OSD
Principal Investigator: Syamal Raychaudhuri, Chief Scientific Officer
Award Amount: $99,964.00
Abstract:
This objective of this study is to develop a robust, field-grade, screening assay for the detection of fever-causing pathogens including Plasmodium sp., Salmonella, Rickettsial sp., Flaviviruses and Leptospira. The test will utilize lateral flow (dipstick) chromatography incorporated into a unique,… More

Field Deployable Diagnostic Test for Active Cutaneous Leishmania and a Test for Latent Infection

Award Year / Program / Phase: 2006 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Raymond Houghton, Director of New Product D
Award Amount: $721,401.00
Abstract:
The proposed immunochromatographic diagnostic test would be a useful rapid diagnostic test for the direct detection of leishmania parasites responsible for cutaneous leishmaniasis in soldiers exhibiting skin lesions.It would have application in detecting leishmania parasites directly from needle… More

A Multiplexed Point-of-Care Assay for the Detection of Enteric Pathogens that Cause Severe Diarrhea in Deployed Soldiers

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: William J. Morrow, Principal Investigator
Award Amount: $69,798.00
Abstract:
The objective of this study is to develop a robust, field-grade, screening assay for the detection of severe diarrheal disease-causing pathogens including E. coli O157, Salmonella spp., Shigella spp., Cryptosporidium spp., Campylobacter spp., Noroviruses, and Rotaviruses. The test will utilize… More

Antigen Detection Assay for Tuberculosis

Award Year / Program / Phase: 2006 / STTR / Phase I
Agency: HHS
Research Institution: FORSYTH INSTITUTE
Principal Investigator: Antonio Camposneto
Award Amount: $386,997.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Antigen detection assay in contrast to conventional serological test, detects disease status and not the host antibody response to the disease etiological agent. It can therefore be used for both diagnosis and disease treatment follow-up purposes. Antigen… More

Development of rapid detection tests for Brucella species

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: William J. Morrow
Award Amount: $607,822.00
Abstract:
DESCRIPTION (provided by applicant): Brucellosis is a re-emerging zoonotic disease that affects humans and a variety of farm animals. As well as a threat to public health it has considerable economic importance. The etiologic agent responsible for human infection, Brucella melitensis, is classified… More

A Multiplexed Assay for the Detection of Pathogens of Military Importance in Sand Flies

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Raymond Houghton, Director of New Product Development
Award Amount: $69,978.00
Abstract:
The objective of this study is to develop a robust, field grade, screening assay for the detection of both leishmania parasites and/or sand fly fever viruses directly in sand flies. The test will utilize a multi-line lateral flow (dipstick) chromatography incorporated into a cassette that enables… More

A Point-of-Care Assay for the Detection of Spotted-fever group and Typhus group Rickettsia.

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: William J. Morrow, Director of New Technology
Award Amount: $69,992.00
Abstract:
The objective of this study is to develop a robust, field-grade, screening assay for the differential diagnosis of infection by Spotted Fevers (e.g. Rocky Mountain Spotted fever, Boutonneuse fever) and Typhus (Epidemic and Endemic forms) causing rickettsial bacteria. Scrub Typhus (Orientia… More

Rapid antigen detection test for Dengue infection

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Raymond Houghton
Award Amount: $684,744.00
Abstract:
DESCRIPTION (provided by applicant): Dengue is a mosquito-transmitted acute viral disease of man caused by the Dengue virus, a member of the flaviviridae family. It is endemic in many parts of the world, particularly tropical and sub-tropical regions and q uite recently there have been outbreaks in… More

Rapid Immunoassay for the Detection of the Bacterium Producing Necrotizing Hepatopancreatitis in Cultured Penaeid Shrimp

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency: USDA
Principal Investigator: Raymond Houghton
Award Amount: $346,000.00
Abstract:
Aquaculture of shrimp is a multi-billion dollar business worldwide. Infection of shrimp grown by aquaculture with the organism leading to Necrotizing HepatoPancreatitis (NHP) is frequently encountered in North, Central and South America and can lead to devastating economic consequences if not… More

A Multiplexed Assay for the Detection of Pathogens of Military Importance in Sand Flies

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Raymond Houghton, Director of New Product D
Award Amount: $729,960.00
Abstract:
Sand flies can cause illnesses such as Leishmaniasis caused by a parasite or sand fly fever due to sand fly fever viruses. The objective of this study is to develop a robust, field grade, screening assay for the detection of both leishmania parasites and/or sand fly fever viruses directly in sand… More

A Multiplexed Point-of-Care Assay for the Detection of Enteric Pathogens that Cause Severe Diarrhea in Deployed Soldiers

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: W. J. Morrow, PI
Award Amount: $724,941.00
Abstract:
The objective of this study is to develop a robust, economical, field-grade, screening assay for the detection of severe diarrhea-causing pathogens including Salmonella spp., E. coli O157, Shigella spp., Cryptosporidium spp., Campylobacter spp., Noroviruses and Rotaviruses. The test will utilize… More

A Point-of-Care Assay for the Detection of Spotted-fever group and Typhus group Rickettsia.

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: John Morrow, Director New Technology A
Award Amount: $709,950.00
Abstract:
The objective of this study is to develop a robust, field-grade, screening assay for the differential diagnosis of infection by Spotted Fevers (e.g. Rocky Mountain Spotted fever, Boutonneuse fever) and Typhus (Epidemic and Endemic forms) causing rickettsial bacteria. Scrub Typhus (Orientia… More

Development of a Point-of-care Assay for the Detection of Rift Valley Fever Virus, a Militarily Important Pathogen of the CENTCOM and AFRICOM Area of

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Syamal Raychaudhuri, Chief Scientific Officer
Award Amount: $69,918.00
Abstract:
The objective of this study is to develop a robust, field grade, screening assay for the detection of RVFV in human blood and sera. The test will utilize a lateral flow (dipstick) chromatography incorporated into a cassette. The proposed immunochromatographic assay would be a very useful screening… More

A Point-of-Care Assay for the Detection of Coxiella Burnetii (Q fever) Infection in Soldiers Deployed to Iraq

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Syamal Raychaudhuri, Chief Scientific Officer
Award Amount: $69,456.00
Abstract:
The objective of this study is to develop a robust, field deployable, and a cost effective rapid screening assay for the detection of Q fever infection caused by Coxiella burnetii using human blood and sera. The test will utilize a lateral flow based immunochromatographic system (dipstick). The… More

Development of a Point-of-care Assay for the Detection of Sand Fly Fever Virus (SFFV), a Militarily Important Pathogen of the CENTCOM, EUCOM and AFRIC

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Raymond Houghton, Director - New Product Development
Award Amount: $69,759.00
Abstract:
Sand fly fever is actually caused by a group of several viruses often termed Sand fly ever viruses (SFFV) and are typically caused by Toscana, Naples and Sicilian viruses. The Toscana virus is confined to Italy and the Mediterranean basin whereas the Naples and Sicilian viruses are more prevalent… More

Geographically robust rapid assay for T. cruzi infection

Award Year / Program / Phase: 2009 / SBIR / Phase II
Agency: HHS
Principal Investigator: Syamal X. Raychaudhuri
Award Amount: $990,081.00
Abstract:
DESCRIPTION (provided by applicant): This application is to develop a standardized and FDA cleared rapid serodiagnostic and confirmatory test for detection of Trypanosoma cruzi (T. cruzi) infections. T. cruzi is transmitted via blood transfusions, is preva lent in Latin America, and is the causative… More

Development of a hand-held, field-deployable multiplex assay for the detection of Chikungunya Virus (CHIKV), West Nile Virus (WNV), and Dengue Virus i

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency / Branch: DOD / OSD
Principal Investigator: Raymond Houghton, Director New Product Development
Award Amount: $99,665.00
Abstract:
Chikungunya an alphavirus, and the West Nile and Dengue Flaviviruses are carried by mosquitoes. While all three initially lead to febrile illness the subsequent clinical outcomes are very different and in some cases dual infections can occur. All three viruses have the potential to lead to fatal… More

Development of a Point-of-care Assay for the Detection of Sand Fly Fever Virus (SFFV), a Militarily Important Pathogen of the CENTCOM, EUCOM and AFRIC

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Raymond Houghton, Director New Product Deve
Award Amount: $729,256.00
Abstract:
Sand flies can cause sand fly fever due to Sand Fly Fever Viruses. The objective of this study is to develop a robust, field grade, screening assay for the detection of both Naples and Sicilian Sand Fly Fever Viruses in human serum. The test will utilize a multi-line lateral flow (dipstick)… More

Developing a Point-of-Care Diagnostic Assay for Leptospirosis

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Stan Morkowski, Senior Scientist
Award Amount: $660,495.00
Abstract:
Leptospirosis outbreaks in US military personnel have been documented in past. Due to the high incidence of this infection in military personnel attending the Jungle Warfare School in Panama, trials of doxycycline prophylaxis and therapy were performed on this population by US Army researchers.… More

Developing a Point-of-Care Diagnostic Assay for Leptospirosis

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Stan Morkowski, President
Award Amount: $118,443.00
Abstract:
The objective of this study is to develop a robust, field deployable, and a cost effective rapid screening assay for the detection of Leptospirosis infection caused by Leptospira pathogens using human blood and sera. The test will utilize a lateral flow based immunochromatographic system (dipstick).… More

Antigen Detection Assay for the Diagnosis of Melioidosis

Award Year / Program / Phase: 2012 / STTR / Phase I
Agency: HHS
Research Institution: UNIVERSITY OF NEVADA RENO
Principal Investigator: Raymond Houghton – 206-344-5821
Award Amount: $599,398.00
RI Contact:
Abstract:
DESCRIPTION (provided by applicant): Burkholderia pseudomallei is a Gram-negative bacterium that is the causative agent of melioidosis. The bacterium causes significant morbidity and mortality in tropical regions and endemic areas are expanding. Melioidosis is difficult to trea and diagnose due to… More

Sensitive and Specific Rapid Diagnostic Test for Acute and Chronic Pancreatitis

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Syamal X. Raychaudhuri – 206-344-5821
Award Amount: $182,430.00
Abstract:
DESCRIPTION (provided by applicant): The very common patient complaint of abdominal pain suggests the diagnosis of pancreatitis. Pancreatitis, however, can be difficult to diagnose or rule out, as the blood-based tests used, serum amylase and lipase, demonstrate suboptimal sensitivity and… More

Development of Blood Donor Screening for Babesiosis

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Raymond Houghton
Award Amount: $149,437.00
Abstract:
Human Babesiosis is primarily caused by Babesia microti an intraerythrocytic parasite with some cases on the US west coast associated with Babesia duncani (WA-1). Typically tick bites are the route of transmission. However, both organisms have been associated with transfusion related infections and… More