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A Multiplexed Point-of-Care Assay for the Detection of Enteric Pathogens that…

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
77443
Program Year/Program:
2006 / SBIR
Agency Tracking Number:
A062-158-0254
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2006
Title: A Multiplexed Point-of-Care Assay for the Detection of Enteric Pathogens that Cause Severe Diarrhea in Deployed Soldiers
Agency / Branch: DOD / ARMY
Contract: W81XWH-07-C-0030
Award Amount: $69,798.00
 

Abstract:

The objective of this study is to develop a robust, field-grade, screening assay for the detection of severe diarrheal disease-causing pathogens including E. coli O157, Salmonella spp., Shigella spp., Cryptosporidium spp., Campylobacter spp., Noroviruses, and Rotaviruses. The test will utilize lateral flow (dipstick) chromatography incorporated into a unique, multiplex cassette that enables the simultaneous screening of multiple analytes. The proposed immunochromatographic assay would be a very useful rapid screening test to assess individuals presenting with diarrhea of likely infectious etiology. In this Phase 1 study we shall evaluate the ability of a panel of antibodies, with specificity for the families of enteric pathogens listed above, to function as the basis of an antigen-capture detection system. We will then construct prototype assays that will be evaluated against samples from individuals with confirmed infections. Further development of the assay would take place in a Phase 2 proposal.

Principal Investigator:

William J. Morrow
Principal Investigator
2063445821
wjwmorrow@inbios.com

Business Contact:

Estela Figueroa
President
2063445821
inbios@aol.com
Small Business Information at Submission:

INBIOS INTERNATIONAL
562 Ist Ave S, Suite 600 Seattle, WA 98104

EIN/Tax ID: 911791824
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No