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Development of a multiplexed point-of-care assay for the detection of…

Award Information

Agency:
Department of Defense
Branch:
Office of the Secretary of Defense
Award ID:
76596
Program Year/Program:
2005 / SBIR
Agency Tracking Number:
O052-H07-3010
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2005
Title: Development of a multiplexed point-of-care assay for the detection of infectious agents causing fever in deployed soldiers.
Agency / Branch: DOD / OSD
Contract: W81XWH-06-C-0095
Award Amount: $99,964.00
 

Abstract:

This objective of this study is to develop a robust, field-grade, screening assay for the detection of fever-causing pathogens including Plasmodium sp., Salmonella, Rickettsial sp., Flaviviruses and Leptospira. The test will utilize lateral flow (dipstick) chromatography incorporated into a unique, multiplex, cassette that enables the simultaneous screening of multiple analytes. The proposed immunochromatographic assay would be a very useful rapid screening test to assess individuals presenting with fevers of likely infectious etiology. In this Phase 1 study we shall evaluate the ability of a panel of antigens, derived from the families of pathogens listed above, to function as the basis of a serological detection system. We will then construct a prototype assay that will be evaluated against sera from individuals with confirmed infections. Further development of the assay would take place in a Phase 2 proposal.

Principal Investigator:

Syamal Raychaudhuri
Chief Scientific Officer
2063445821
raychaud@inbios.com

Business Contact:

Estela Figueroa
President
2063445821
inbios@aol.com
Small Business Information at Submission:

INBIOS INTERNATIONAL
562 Ist Ave S, Suite 600 Seattle, WA 98104

EIN/Tax ID: 911791824
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No