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Advanced Detection Technologies for Biochips

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
71224
Program Year/Program:
2004 / STTR
Agency Tracking Number:
AI060057
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
INDEVR, INC.
2100 Central Ave, Suite 106 BOULDER, CO -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2004
Title: Advanced Detection Technologies for Biochips
Agency: HHS
Contract: 1R41AI060057-01
Award Amount: $932,297.00
 

Abstract:

DESCRIPTION (provided by applicant): The long-term objective of the proposed work is the development of innovative detection technologies for biochips (a.k.a. DNA microarrays). It is envisioned that the proposed technologies will enable the application of biochips to biodefense, particularly when a rapid and reliable diagnostic screen is required in the field. The Specific Aims of the proposed work are 1) development of an on-chip signal amplification technique that does not require enzymes, and 2) development of an inexpensive field-portable microarray reader to be used in combination with on-chip amplification. In order to focus initial efforts we have chosen to work in conjunction with NIH funded scientists who are developing a specific application, an influenza A biochip. Because influenza A is an easily transmitted, primarily airborne pathogen, and because this virus can be genetically engineered into novel forms, it represents a serious biodefense concern. In addition, the influenza A virus has a significant impact on human health, with an estimated 500,000 and 1,000,000 deaths worldwide each year, and worldwide surveillance is essential. Finally, influenza A can serve as an excellent model system for development and thorough testing of on-chip signal amplification and a field portable microarray reader.

Principal Investigator:

Kathy L. Rowlen
3034498146
rowlen2@colorado.edu

Business Contact:


3034029100
Small Business Information at Submission:

INDEVR, LLC
2100 Central Ave Suite 106 BOULDER, CO 80301

EIN/Tax ID: 680524446
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
UNIVERSITY OF COLORADO AT BOULDER
UNIVERSITY OF COLORADO BOULDER
Boulder, CO 80309
RI Type: Nonprofit college or university