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Company Information:
Name:
LIBREDE, INC.
Address:
14819 Sutton St.
Sherman Oaks, CA 91403-4146
Sherman Oaks, CA 91403-4146
Located in HUBZone:
No
Woman-Owned:
No
Minority-Owned:
No
URL:
N/A
Phone:
N/A
Award Totals:
Award List:
Development of a disposable shippable chip for high throughput ion channel screen
Award Year / Program / Phase:
2009 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Jason L. Poulos
Award Amount:
$130,465.00
Abstract:
DESCRIPTION (provided by applicant): Ion channels are important drug targets and unintended drug interactions with ion channels are also of critical importance, requiring the screening of all drug candidates. Conventional high throughput screening processe
s for soluble proteins are problematic to… More
Instrumentation Development for Parallel Measurement of an Ion Channel Array Chip
Award Year / Program / Phase:
2010 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Jason Poulos
Award Amount:
$128,332.00
Abstract:
DESCRIPTION (provided by applicant): Electrophysiological assays of ion channels for pharmaceutical discovery and safety screening are problematic to perform in high throughput because the ion channels must be incorporated into a lipid bilayer membrane to
enable measurement of their ionic… More
SBIR Phase I: Development of new materials for a low cost high throughput ion channel measurement platform
Award Year / Program / Phase:
2010 / SBIR / Phase I
Agency:
NSF
Principal Investigator:
Jason Poulos, PhD
Award Amount:
$149,770.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project will support the development of a novel ion channel measurement platform. Ion channels are important in a wide range of physiological processes including cardiac and neural activity. The technology is centered on inexpensively… More
Droplet-based artificial membrane technology for high throughput cell-free ion ch
Award Year / Program / Phase:
2011 / SBIR / Phase I
Agency:
HHS
Principal Investigator:
Jason Poulos – 858-349-6779
Award Amount:
$163,750.00
Abstract:
DESCRIPTION (provided by applicant): Ion channels pharmaceutical discovery and safety screening is slow and expensive and as a result, there are currently no high quality, high throughput assays for ion channel screening. Librede Inc. is developing alternative cell-free technologies for ion channel… More
Development of a disposable cell-free ion channel measurement platform for hERG s
Award Year / Program / Phase:
2011 / SBIR / Phase II
Agency:
HHS
Principal Investigator:
Jason Poulos – 858-349-6779
Award Amount:
$777,827.00
Abstract:
DESCRIPTION (provided by applicant): Assaying ion channels for pharmaceutical discovery and safety screening is problematic to perform in high throughput because the ion channels must be incorporated into a cell membrane to allow measurement of their ionictransport to determine their functionality.… More
High throughput cell-free ion channel screening workstation
Award Year / Program / Phase:
2012 / SBIR / Phase II
Agency:
HHS
Principal Investigator:
Jason Poulos – 858-349-6779
Award Amount:
$1,552,831.00
Abstract:
DESCRIPTION (provided by applicant): Ion channels are important drug targets-present in every cell, they play key roles in a wide range of physiological processes including the cardiac cycle and neural activity. As a result, unintended drug interactions with ion channels are also of critical… More
SBIR Phase I: Development of a 32 site ion channel measurement consumable
Award Year / Program / Phase:
2012 / SBIR / Phase I
Agency:
NSF
Principal Investigator:
Jason Poulos
Award Amount:
$149,995.00
Abstract:
This Small Business Innovation Research Phase I project is aimed at developing improved technology for drug discovery and safety screening of ion channels. Ion channels are present in every cell and play key roles in a wide range of physiological processes including the cardiac cycle and neural… More