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Company Information:

Company Name: LIBREDE, INC.
City: Sherman Oaks
State: CA
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $722,312.00 5
SBIR Phase II $2,330,658.00 2

Award List:

Development of a disposable shippable chip for high throughput ion channel screen

Award Year / Program / Phase: 2009 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jason L. Poulos
Award Amount: $130,465.00
Abstract:
DESCRIPTION (provided by applicant): Ion channels are important drug targets and unintended drug interactions with ion channels are also of critical importance, requiring the screening of all drug candidates. Conventional high throughput screening processe s for soluble proteins are problematic to… More

Instrumentation Development for Parallel Measurement of an Ion Channel Array Chip

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jason Poulos
Award Amount: $128,332.00
Abstract:
DESCRIPTION (provided by applicant): Electrophysiological assays of ion channels for pharmaceutical discovery and safety screening are problematic to perform in high throughput because the ion channels must be incorporated into a lipid bilayer membrane to enable measurement of their ionic… More

SBIR Phase I: Development of new materials for a low cost high throughput ion channel measurement platform

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: NSF
Principal Investigator: Jason Poulos, PhD
Award Amount: $149,770.00
Abstract:
This Small Business Innovation Research (SBIR) Phase I project will support the development of a novel ion channel measurement platform. Ion channels are important in a wide range of physiological processes including cardiac and neural activity. The technology is centered on inexpensively… More

Droplet-based artificial membrane technology for high throughput cell-free ion ch

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jason Poulos – 858-349-6779
Award Amount: $163,750.00
Abstract:
DESCRIPTION (provided by applicant): Ion channels pharmaceutical discovery and safety screening is slow and expensive and as a result, there are currently no high quality, high throughput assays for ion channel screening. Librede Inc. is developing alternative cell-free technologies for ion channel… More

Development of a disposable cell-free ion channel measurement platform for hERG s

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: Jason Poulos – 858-349-6779
Award Amount: $777,827.00
Abstract:
DESCRIPTION (provided by applicant): Assaying ion channels for pharmaceutical discovery and safety screening is problematic to perform in high throughput because the ion channels must be incorporated into a cell membrane to allow measurement of their ionictransport to determine their functionality.… More

High throughput cell-free ion channel screening workstation

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: HHS
Principal Investigator: Jason Poulos – 858-349-6779
Award Amount: $1,552,831.00
Abstract:
DESCRIPTION (provided by applicant): Ion channels are important drug targets-present in every cell, they play key roles in a wide range of physiological processes including the cardiac cycle and neural activity. As a result, unintended drug interactions with ion channels are also of critical… More

SBIR Phase I: Development of a 32 site ion channel measurement consumable

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: NSF
Principal Investigator: Jason Poulos
Award Amount: $149,995.00
Abstract:
This Small Business Innovation Research Phase I project is aimed at developing improved technology for drug discovery and safety screening of ion channels. Ion channels are present in every cell and play key roles in a wide range of physiological processes including the cardiac cycle and neural… More