BIOABSORBABLE GLASS FOR RADIATION TREATMENT OF ARTHRITIS

Award Information

Agency: Department of Health and Human Services	Branch: N/A	Award ID: 13687	Program Year/Program: 1993 / SBIR
Agency Tracking Number: 13687	Solicitation Year: N/A	Solicitation Topic Code: N/A	Solicitation Number: N/A

Small Business Information: MO-SCI Corporation
4040 Hypoint North Rolla, MO -
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Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No

Phase 2: Fiscal Year: 1993

Title: BIOABSORBABLE GLASS FOR RADIATION TREATMENT OF ARTHRITIS

Agency: HHS

Contract: N/A

Award Amount: $499,936.00

Abstract:
PRESENT TREATMENT OF RHEUMATOID ARTHRITIS IS PERFORMED BY SEVERAL METHODS, WHICH INCLUDE ANTI-INFLAMMATORY AGENTS, STEROIDS, IMMUNOSUPPRESSIVE AND CYTOTOXIC AGENTS, RADIATION TREATMENT BY BEAM METHOD, AND SURGERY. EACH METHOD HAS ITS DRAWBACKS. OF THESE METHODS, RADIATION BEAM TREATMENT HAS BEEN SHOWN TO SUPPRESS THE INFLAMED SYNOVIUM AND PALLIATE THE PATIENT'S PAIN. THERE ARE, HOWEVER, ADVERSE EFFECTS TO SURROUNDING HARD AND SOFT TISSUE. THE OBJECTIVE OF THIS RESEARCH IS TO DEVELOP A GLASS MATRIX CONTAINING AN ACTIVATABLE BETA-EMITTING ISOTOPE WITH A TREATMENT DISTANCE OF 1 TO 3 MM. WHEN INJECTED INTO THE JOINT, THE MICROSPHERES WILL PERMIT A LOCALIZED IRRADIATION OF THE DISEASED AREA, LEADING TO RESULTS COMPARABLE TO THAT PROVIDED BY SURGERY. ONCE THE RADIOACTIVITY HAS DECAYED, THE MICROSPHERES WILL DISSOLVE AND BE ABSORBED INTO THE BODYOVER A 3- TO 6-MONTH PERIOD.

Principal Investigator:
John B Koen
3143642338

Business Contact:

Small Business Information at Submission:

Mo-sci Corp.
Twitty Industrial Pk Mead Bldg Po Box 2 Rolla, MO 65401

EIN/Tax ID:

DUNS: N/A

Number of Employees: N/A

Woman-Owned: No

Minority-Owned: No

HUBZone-Owned: No