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Kidney Multiphoton Analysis of Therapeutic Agents

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
85559
Program Year/Program:
2007 / STTR
Agency Tracking Number:
DK076478
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
INPHOTON, LLC
1213 ALDERLEY RD INDIANAPOLIS, IN -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2007
Title: Kidney Multiphoton Analysis of Therapeutic Agents
Agency: HHS
Contract: 1R41DK076478-01A1
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION (provided by applicant): The integrated scientific team of INphoton, LLC will develop standard operating procedures for intravital multiphoton microscopy assays quantifying fluorescent drug delivery, cellular uptake, intracellular distribution, metabolism, and physiologic/therapeutic effects within the kidney of live rats. Refinement of some existing assays will be necessary for commercial utilization. The resulting products will enable INphoton to extend commercial services to pharmaceutical an d biotech companies to enhance preclinical evaluation of potential products. INphoton, LLC will commercialize multiphoton microscopy for preclinical drug evaluation in the kidney. This will greatly aid evaluation of a potential therapeutic agent's cellular location, functional effects and adverse affects. Since this is not possible with other imaging modalities, this approach complements and extends existing imaging technologies.

Principal Investigator:

Kenneth W. Dunn
3172780436
KWDUNN@IUPUI.EDU

Business Contact:


satkinso@iupui.edu
Small Business Information at Submission:

INPHOTON, LLC
INPHOTON, LLC 1213 ALDERLEY RD INDIANAPOLIS, IN 46260

EIN/Tax ID: 113430789
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
INDIANA UNIVERSITY
INDIANA UNIVERSITY
BRYAN HALL
BLOOMINGTON, IN 47405 4899
RI Type: Nonprofit college or university