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Company Information:

Company Name: INSILICOS
City: SEATTLE
State: WA
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,872,888.00 8
SBIR Phase II $3,148,550.00 3
STTR Phase I $100,000.00 1

Award List:

STTR Phase I: Analysis of Comprehensive Two Dimensional Gas Chromatography with Mass Spectrometry for High-Throughput Metabolomics

Award Year / Program / Phase: 2003 / STTR / Phase I
Agency: NSF
Research Institution: University of Wisconsin-Madison
Principal Investigator: Erik Nilsson
Award Amount: $100,000.00
RI Contact: N/A
Abstract:
This Small Business Technology Transfer (STTR) Phase I project is to develop an intelligent prosthetic foot that reduces the energy consumption of walking in amputees. Commercial prostheses use passive mechanisms to provide articulation, cushioning against heel impact, and elastic energy return;… More

Pattern Recognition Software for Single Cell Proteomics

Award Year / Program / Phase: 2004 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Nilsson
Award Amount: $99,911.00
Abstract:
DESCRIPTION (provided by applicant): A new method is proposed for analyzing proteins in single cells. Advanced analytical techniques and a unique software platform are used to classify samples processed on a single-cell proteomics instrument. The research team includes seasoned experts in… More

Heterogeneous Proteomics Data Analysis and Management

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Nilsson
Award Amount: $396,715.00
Abstract:
DESCRIPTION (provided by applicant): Software tools for statistical analysis arid comparison of proteomics data is proposed. Using these tools, data can be compared from different research groups using different experimental techniques, analytical instrumentation, peptide search engines, and… More

Pattern Recognition Mass Spectrometry in the Diagnosis of Heart Disease

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Bryan Prazen
Award Amount: $400,000.00
Abstract:
DESCRIPTION (provided by applicant): This proposal investigates a novel approach to high-throughput proteomics. Proteins bound to specific blood components, such as HDL (high-density lipoprotein), are examined via mass spectrometry (MS). The resulting data are processed with a novel pattern… More

A collaboration platform for proteomics biomarker analysis

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency: HHS
Principal Investigator: Erik J. Nilsson
Award Amount: $1,196,978.00
Abstract:
DESCRIPTION (provided by applicant): A novel computational analysis platform is proposed, which enables collaboration in the discovery and characterization of proteomics biomarkers. The proposed system is a broad academic-commercial collaboration, integrat es several prominent proteomics efforts,… More

Scalable Secure Sharable Computation Platform for Proteomics Data Analysis

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Nilsson
Award Amount: $188,555.00
Abstract:
DESCRIPTION (provided by applicant): A novel distribution platform for an open source proteomic database and computational analysis system is proposed. The proposed platform will enable inter-institutional collaboration in the study of biological mechanism s and measurement of complex protein… More

High-throughput Epistasis Screening Using Genetical Genomics

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Mark L. Seligman
Award Amount: $181,857.00
Abstract:
DESCRIPTION (provided by applicant): High-throughput Epistasis Screening using Genetical Genomics A fast software tool is proposed for identifying potential sets of interacting genes involved in human disease pathways. A meta-analysis of marker and express ion-trait studies is performed using… More

Cloud-computing MapReduce toSearch for Post-Translationally Modified Peptides

Award Year / Program / Phase: 2010 / SBIR / Phase I
Agency: HHS
Principal Investigator: Erik J. Nilsson
Award Amount: $179,499.00
Abstract:
DESCRIPTION (provided by applicant): A enhancement to the popular peptide search engine X Tandem is proposed, to allow it to run on new super-scalable MapReduce computer clusters. This will allow much faster and less-expensive operation, allowing proteomic s researchers to routinely search for… More

Scalable Learning with Ensemble Techniques and Parallel Computing

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Erik J. Nilsson
Award Amount: $751,572.00
Abstract:
DESCRIPTION (provided by applicant): The ability to conduct basic and applied biomedical research is becoming increasingly dependent on data produced by new and emerging technologies. This data has an unprecedented amount of detail and volume. Researchers are therefore dependent on computing and… More

HDL Proteomics for Heart Disease Detection

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Bryan Prazen
Award Amount: $1,200,000.00
Abstract:
DESCRIPTION (provided by applicant): Heart disease is the leading cause of death in the western societies. The plasma level of high density lipoprotein cholesterol (HDL-C), the good form of cholesterol, is negatively correlated with the risk of heart disea se, myocardial infarction, and coronary… More

GPU-accelerated Peptide Search

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: HHS
Principal Investigator: Brian Pratt – 206-979-4832
Award Amount: $203,600.00
Abstract:
DESCRIPTION (provided by applicant): The use of Graphics Processing Unit (GPU) devices is proposed to increase the speed of peptide search by as much as an order of magnitude. Peptide search engines perform the most computation-intensive task in shotgun proteomics. This proposal is to speed up… More

Parsimonious Models for Survival Data

Award Year / Program / Phase: 2012 / SBIR / Phase I
Agency: HHS
Principal Investigator: Chris Fraley – 206-979-4832
Award Amount: $222,751.00
Abstract:
DESCRIPTION (provided by applicant): This Small Business Innovation Research project addresses the problem of biomarker detection in clinical and high-throughput data. The objective is to investigate new approaches for deter- mining, from data consisting of many possibly irrelevant or redundant… More