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ELECTROPHORETIC DESORPTION FOR THE REGENERATION OF IMMUNOLOGICALLY ACTIVE…

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
5977
Program Year/Program:
1989 / SBIR
Agency Tracking Number:
5977
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Integrated Chemical Sensors
44 Mechanic St Newton, MA 02164
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1989
Title: ELECTROPHORETIC DESORPTION FOR THE REGENERATION OF IMMUNOLOGICALLY ACTIVE SENSOR SURFACES
Agency / Branch: DOD / ARMY
Contract: N/A
Award Amount: $189,478.00
 

Abstract:

THE PURPOSE OF THIS PROGRAM IS TO DETERMINE IF THE PROVEN TECHNIQUE OF ELECTROPHORETIC DESORPTION (ED) CAN BE USED TO EFFECTIVELY REGENERATE IMMUNOLOGICALLY ACTIVE SURFACES SUITABLE FOR USE WITH MICROELECTRONIC BIOSENSORS. PREVIOUS WORK ON ED WAS DONE WITH CHROMATOGRAPHIC GELS, NOT PLANAR SURFACES. A SYSTEM FOR ED OF PLANAR SENSOR SURFACES WILL BE DEVELOPED; THE SYSTEM WILL BE OPTIMIZED AND EVALUATED FOR THE EFFICIENCY OF REGENERATION AND THE REUSABILITY OF THE REGENERATED SURFACE. FACTORS TO BE CONSIDERED INCLUDE: ELECTRIC FIELD GEOMETRIES, POWER REQUIREMENTS, PH, IONIC STRENGTH, TIME REQUIREMENTS, EFFICIENCY OF ELUTION AND REUSABILITY OF THE REGENERATED SURFACE. THE COMBINATION OF THIS TECHNIQUE WILL CHAOTROPIC AGENTS AND SURFACTANTS WILL ALSO BE STUDIED. THE REMOVAL OF BOTH LARGE AND SMALL MOLECULES WILL BE STUDIED. THE MODEL SYSTEMS WILL BE BASED ON ICSC SAW SENSORS. IT IS EXPECTED THAT THE INFORMATION GAINED FROM THIS STUDY SHOULD BE APPLICABLE TO OTHER ELECTRONIC AND OPTICAL MICRO-SENSOR SYSTEMS AND RECEPTOR-BASED BIOSENSORS WHICH WILL BE STUDIED IN PHASE II OF THIS PROGRAM.

Principal Investigator:

Dr Glenn J Bastiaans
6179656950

Business Contact:

Small Business Information at Submission:

Integrated Chemical Sensors
44 Mechanic St Newton, MA 02164

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No