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Chronic Telemetric Biofluid Flow Monitoring Device

Award Information

National Aeronautics and Space Administration
Award ID:
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Integrated Sensing Systems Incorporated
391 Airport Industrial Drive Ypsilanti, MI 48198-7812
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2003
Title: Chronic Telemetric Biofluid Flow Monitoring Device
Agency: NASA
Contract: NAS3-03032
Award Amount: $69,990.00


Currently, no method exists for continuously, noninvasively monitoring flow in the vascular and other biofluidic systems. To facilitate the study of short- and long-term effects of gravity on biofluidic systems, ISSYS proposes to develop an innovative technology for direct, chronic measurement of flow in the vascular system. The proposed effort will ultimately develop a stent-based, telemetric, implantable flow monitor. Once implanted, flow data may be read noninvasively through magnetic telemetry, using a compact readout unit. This system will take advantage of state-of-the-art Microelectromechanical Systems (MEMS) technology to develop a highly stable device for real-time, noninvasive collection of flow data. The core technology will be based on a high-sensitivity capacitive MEMS pressure sensor developed by ISSYS. The system will be fully spaceworthy, itself being immune to the effects of both microgravity and hypergravity as well as shock and vibration. Once the wireless, batteryless, stent-based flow sensor is delivered by catheter, flow data may be taken continuously by means of noninvasive magnetic telemetry. Phase I for this project will demonstrate the feasibility of calculating flow rates from measured pressure gradients, after which a subsequent Phase II effort would develop the complete implantable monitor and associated readout technology.

Principal Investigator:

Susan (Yafan) Zhang,

Business Contact:

Nader Najafi
Business Official
Small Business Information at Submission:

Integrated Sensing Systems, Inc. (ISSYS)
391 Airport Industrial Dr. Ypsilanti, MI 48198

EIN/Tax ID: 383221564
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No