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SBIR Phase I: Microfluidic Gas/Liquid Two-Phase Sensing and Compensation

Award Information

Agency:
National Science Foundation
Branch:
N/A
Award ID:
84704
Program Year/Program:
2007 / SBIR
Agency Tracking Number:
0710718
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Integrated Sensing Systems Incorporated
391 Airport Industrial Drive Ypsilanti, MI 48198-7812
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2007
Title: SBIR Phase I: Microfluidic Gas/Liquid Two-Phase Sensing and Compensation
Agency: NSF
Contract: 0710718
Award Amount: $100,000.00
 

Abstract:

This Small Business Innovation Research Phase I research project addresses research and development into two-phase microfluidic behavior in resonating microtubes. Gas phase, or air bubble detection in intravenous drug lines is critical to preventing air embolisms and even death. Two-phase detection and damping problems have been reported in macroscopic Coriolis mass flow meters and in MEMS-based resonant tubes. There are experimental indications that microbubbles may be nucleating ultrasonically and then growing while attached to the interior of microfluidic resonant tubes. It is proposed to utilize resonant microtube technology to investigate the impact of gas phase formation and the gas liquid interaction and compensation for the associated damping as it applies to Coriolis mass flow and density measurement. This innovative research will improve bubble detection in liquid medication delivery systems and overcome problems experienced with two-phase damping in resonant sensing systems. The initial test bed will be for a MEMS-based, microfluidic drug delivery system. A new method of performing cell lysis and DNA analysis on small samples may be realized if cavitation can be controlled in the microtubes. The final goal is to successfully enable the commercialization of microfluidic Coriolis mass flow sensors and chemical concentration meters for industrial and medical applications. For this to happen the problems associated with gas phase detection and the two-phase damping must be overcome. This research has the potential of introducing a new means of detecting and measuring a second, gas phase in a liquid stream.

Principal Investigator:

Douglas E. Sparks
DEng
7345479896
dsparks@mems-issys.com

Business Contact:

Douglas E. Sparks
DEng
7345479896
dsparks@mems-issys.com
Small Business Information at Submission:

Integrated Sensing Systems Incorporated
391 Airport Industrial Drive Suite 202 Ypsilanti, MI 48198

EIN/Tax ID: 383221564
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No