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Company Information:

Company Name: INTELLIGENT BIO-SYSTEMS, INC.
City: Waltham
State: MA
Zip+4: -
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $1,315,802.00 6
SBIR Phase II $10,143,809.00 5
STTR Phase II $933,083.00 1

Award List:

Analyzing Multiplexed Amplicons for Advanced Sequencing

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Steven J. Gordon
Award Amount: $79,993.00
Abstract:
Although the sequence of the human genome was substantially completed in 2002, there is still a huge need for the production of DMA sequence data. The number of organisms and individuals which may be sequenced is still significantly constrained by the lengthy time, high complexity and exorbitant… More

Streamlined Template Preparation for Advanced Sequencing Methods

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Steven J. Gordon
Award Amount: $161,067.00
Abstract:
DESCRIPTION (provided by applicant): Although the sequence of the human genome was substantially completed in 2002, there is still a huge need for the production of DNA sequence data. In particular, the genome within carcinogenic tissues is believed to vary widely from a normal genome, both in… More

Ordered Arrays for Advanced Sequencing Systems

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency: HHS
Principal Investigator: Steven J. Gordon
Award Amount: $158,687.00
Abstract:
DESCRIPTION (provided by applicant): Although the sequence of the human genome was substantially completed a few years ago, there is still a huge need for the production of DNA sequence data. The number of organisms and individuals which may be sequenced is still significantly constrained by the… More

Novel Diagnostic Sequencing System for HIV Resistance Testing

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jerzy Olejnik
Award Amount: $600,000.00
Abstract:
DESCRIPTION (provided by applicant): As of 2003 the CDC estimated that there were approximately 1.1 million persons in the U.S. infected with HIV- 1 and about 40,000 new cases are diagnosed each year. During the mid-to-late 1990s, advances in treatment sl owed the progression of HIV to AIDS and… More

Digital Gene Expression for Cancer

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Steven J. Gordon
Award Amount: $153,481.00
Abstract:
DESCRIPTION (provided by applicant): Although precise knowledge of the genomic sequence within neoplastic tissues can be an indicator for treatment, for example the erbB-2 receptor gene (Her-2) for breast cancer, such correlations are few and often do not adequately define tumor subtypes important… More

Streamlined Template Preparation for Advanced Sequencing Methods

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency: HHS
Principal Investigator: Steven J. Gordon
Award Amount: $1,471,848.00
Abstract:
DESCRIPTION (provided by applicant): The advent of next-generation sequencing technologies is allowing researchers to perform studies and make discoveries which previously were not economically or technically feasible. For example, precise knowledge of th e genomic sequence within neoplastic… More

Novel Cleavable Nucleotides for DNA Sequencing by Synthesis

Award Year / Program / Phase: 2008 / SBIR / Phase I
Agency: HHS
Principal Investigator: Jerzy Olejnik
Award Amount: $162,574.00
Abstract:
DESCRIPTION (provided by applicant): Intelligent Bio-Systems is developing a high-speed, low-cost DNA sequencing-by-synthesis (SBS) system which is based on the use of cleavable fluorescent nucleotides with reversible terminator technology. The cleavable l inkers utilized in these nucleotides enable… More

Alkoxylamine nucleosides for sequencing by synthesis

Award Year / Program / Phase: 2008 / STTR / Phase II
Agency: HHS
Research Institution: N/A
Principal Investigator: Steven A. Benner
Award Amount: $933,083.00
RI Contact: N/A
Abstract:
DESCRIPTION (provided by applicant): Sequencing during synthesis (SdS) is an architecture for massively parallel DNA sequencing that has the strong potential of lowering the cost of sequencing enough to allow individuals access to their own genetic heritag e as a way of personalizing their medical… More

Ordered Arrays for Advanced Sequencing Systems

Award Year / Program / Phase: 2010 / SBIR / Phase II
Agency: HHS
Principal Investigator: Steven J. Gordon
Award Amount: $2,645,801.00
Abstract:
DESCRIPTION (provided by applicant): The advent of next-generation sequencing technologies is allowing researchers to perform studies and make discoveries which previously were not economically or technically feasible. Thus far, however, higher-throughpu t next-generation sequencing systems are… More

Novel Diagnostic Sequencing System for HIV Resistance Testing

Award Year / Program / Phase: 2011 / SBIR / Phase II
Agency: HHS
Principal Investigator: Jerzy Olejnik – 781-354-3354
Award Amount: $2,952,955.00
Abstract:
DESCRIPTION (provided by applicant): As of 2008 the CDC estimated that there were approximately 1.1 million persons in the U.S. infected with HIV- 1 and about 56,000 new cases are diagnosed each year. During the mid-to-late 1990s, advances in treatment slowed the progression of HIV to AIDS and… More

Low-Cost Digital Gene Expression System

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: HHS
Principal Investigator: Steven J. Gordon – 781-466-8050
Award Amount: $1,597,096.00
Abstract:
DESCRIPTION (provided by applicant): As the second most common cause of death in the US, cancer is caused by random mutations in an organism's genome. Although precise knowledge of the genomic sequence within neoplastic tissues can be an indicator for treatment, for example the erbB-2 receptor… More

NOVEL CLEAVABLE NUCLEOTIDES FOR DNA SEQUENCING BY SYNTHESIS

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: HHS
Principal Investigator: Jerzy Olejnik – 781-354-3354
Award Amount: $1,476,109.00
Abstract:
DESCRIPTION (provided by applicant): The objective of this proposal is to further optimize Sequencing By Synthesis (SBS) chemistry to power a highly-sensitive, low-cost, sequencing system for clinical diagnostic sequencing called PinPoint MINI. A single human exome at 30 x coverage will be sequenced… More