SBIR Phase I: An Electrowetting Microfluidic Device for Bioassays
This Small Business Innovation Research (SBIR) Phase I project proposes to demonstrate the
feasibility of an innovative approach to fabricating microfluidic devices for bioassays
within a Micro Total Analytical System (`TAS) format. The device will be based on
electrowetting on dielectric (EWOD) technology, and will offer potential lower fabrication
costs for numerous applications. The EWOD approach for microfluidics is to transport
droplets, as opposed to continuous liquids, along an electronically programmable path on a
large array of driving micropads, rather than through fixed microchannels. The EWOD
mechanism is inherently effective for droplets, and appears well suited for open two
dimensional microfluidic array applications, and use with physiological fluids. An EWOD
microfluidic device will be capable of manipulating droplets of physiological fluids.
Feasibility will be demonstrated by implementing a heterogeneous chemiluminescent
immunoassay for ferritin in blood serum on an EWOD device.
The main commercial application of this project will be in the area of medical diagnostics.
Additional applications would include bioassays for homeland security and environmental
monitoring and for sampling systems to support DNA and protein microarray assays.
Small Business Information at Submission:
Principal Investigator:Glenn Bastiaans
Intelligent Optical Systems Inc
2520 W. 237th Street Torrance, CA 90505
Number of Employees: