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IN SITUATIONS OF LOCALIZED DISEASE IT MAY BE DIFFICULT OR IMPRACTICAL FOR…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
3139
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
3139
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
International Biomedics Inc
1631 220th Ave Se Bothell, WA 98021
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: IN SITUATIONS OF LOCALIZED DISEASE IT MAY BE DIFFICULT OR IMPRACTICAL FOR PHYSICIANS TO EXTRICATE ASSAY SAMPLES OR PERFORM TESTS SPECIFICALLY DEFINING PATHOLOGIC STATUS AT GIVEN LESIONS.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

IN SITUATIONS OF LOCALIZED DISEASE IT MAY BE DIFFICULT OR IMPRACTICAL FOR PHYSICIANS TO EXTRICATE ASSAY SAMPLES OR PERFORM TESTS SPECIFICALLY DEFINING PATHOLOGIC STATUS AT GIVEN LESIONS. INFLAMMATORY SITES OF PERIODONTAL LESIONS ARE A REPRESENTATIVE PROBLEM. OUR OBJECTIVE IS TO DEVELOP A BIOPROBE-ASSAY SYSTEM USEFUL IN THE DIAGNOSIS AND EVALUATION OF PERIODONTAL DISEASE. THE SPECIFIC AIM IS TO CREATE A PROBE FOR THE PERIODONTOPATHOGEN ACTINOBACILLUS ACTINOMYCETEMCOMITANS (AA). THE ASSAY SYSTEM WILL UTILIZE A SMALL PROBE COATED WITH ANTIBODY TO AA MICROBES, WHICH WHEN PLACED AT AN INFECTED SITE WILL SPECIFICALLY BIND AA ORGANISMS. BOUND AA WILL BE IMMUNOLOGICALLY PROCESSED IN VITRO TO PRODUCE AN OPTICAL SIGNAL QUANTITATIVELY THE ASSAY WILL BE RAPID AND SIMPLE, SUITABLE FOR GENERAL OFFICE PRACTICE. IN CONTRAST TO CURRENT METHODS, IT WILL YIELD OBJECTIVE MEASURES WHICH AID IN DIAGNOSIS AND EVALUATION OF ACTIVITY WITHIN LESIONS, THUS ENABLING PHYSICIANS TO PROVIDE BETTER HEALTH CARE. PHASE I RESEARCH FOCUSES ON DEVELOPMENT AND CHARACTERIZATION OF THE ASSAY SYSTEM. CORRELATION WITH CLINICAL DIAGNOSIS WILL BE EXAMINED IN PHASE II. THE SYSTEM HAS POTENTIAL FOR MULTIPLE APPLICATIONS USING SIMILAR PROBES WITH ANTIBODIES TO OTHER ENTITIES.

Principal Investigator:

David l. putnam
PRINCIPAL INVESTIGATOR
648522004

Business Contact:

Small Business Information at Submission:

International Biomedics, Inc.
1631 220th Se Bothell, WA 98021

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No