USA flag logo/image

An Official Website of the United States Government

RAPID METHODS OF DIAGNOSIS IN SUCH AREAS AS CANCER ETIOLOGY, SUSCEPTIBILITY,…

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
3193
Program Year/Program:
1985 / SBIR
Agency Tracking Number:
3193
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
International Biotechnologies
Box 1565 275 Winchester Avenue New Haven, CT 06511
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1985
Title: RAPID METHODS OF DIAGNOSIS IN SUCH AREAS AS CANCER ETIOLOGY, SUSCEPTIBILITY, AND THE IDENTIFICATION OF GENETICALLY HERITABLE DISEASES CURRENTLY INVOLVE A NUMBER OF TIME-CONSUMING STEPS.
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

RAPID METHODS OF DIAGNOSIS IN SUCH AREAS AS CANCER ETIOLOGY, SUSCEPTIBILITY, AND THE IDENTIFICATION OF GENETICALLY HERITABLE DISEASES CURRENTLY INVOLVE A NUMBER OF TIME-CONSUMING STEPS. ELECTROBLOTTING IS A TECHNIQUE WHEREBY ELECTRIC FIELDS ARE USED TO TRANSFER MACROMOLECULES FROM GELS TO SUPPORT MEMBRANES. THE TECHNIQUE CAN BE USED IN STUDIES INVOLVING DNA (SOUTHERN RECENTLY, A NEW BLOTTING SYSTEM WAS INVENTED AT INTERNATIONAL BIOTECHNOLOGIES, INC. WHEREIN QUANTITATIVE DNA BLOTS OF EXTRAORDINARILY ACCURATE REPRODUCIBILITY COULD BE ACCOMPLISHED IN SECONDS. THIS IS IN CONTRAST TO THE CURRENT BLOT- TING METHODS REQUIRING FROM 2 TO 12 HOURS. IBI (J. H. KREISHER, INVENTOR) HAS RECEIVED ACCEP- TANCE NOTICE FOR A PATENT ON THIS METHOD OF ELECTROBLOTTING. THIS APPLICATION WOULD PROVIDE FUNDS FOR THE DEVELOPMENT OF OPTIONAL METHODS AND CONDITIONS FOR BLOTTING ONTO SOLID SUPPORT MEMBRANES. PHASE II ACTIVITIES WILL CONCENTRATE ON TRANSFERRING EITHER RNA OR PROTEIN ONTO THESE SOLID MEMBRANES AND WILL BEGIN TO INCORPORATE THIS TECHNIQUE WITH COMPATIBLE ELECTROPHORETIC GEL MATERIALS AND METHODS INTO A COMMERCIALLY MARKETABLE RESEARCH AND DIAGNOSTIC TOOL.

Principal Investigator:

John h. kreisher
PRINCIPAL INVESTIGATOR
2035623878

Business Contact:

Small Business Information at Submission:

International Biotechnologies,
275 Winchester Avenue New Haven, CT 06506

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No