USA flag logo/image

An Official Website of the United States Government

Company Information:

Company Name: INTRALYTIX INC
City: Baltimore
State: MD
Zip+4: 21201-8603
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phone: (410) 625-3813

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $539,202.00 4
SBIR Phase II $1,179,858.00 2
STTR Phase I $299,917.00 3
STTR Phase II $749,969.00 1

Award List:

N/A

Award Year / Program / Phase: 2000 / STTR / Phase I
Agency: HHS
Research Institution: Baltimore Research & Edu Foundation
Principal Investigator:
Award Amount: $99,929.00
RI Contact: N/A

Development of a phage-based technology for eliminating or significantly reducing contamination of fruits and vegetables with E. coli O157:H7

Award Year / Program / Phase: 2006 / SBIR / Phase I
Agency / Branch: DOD / ARMY
Principal Investigator: Alexander Sulakvelidze, Chief Scientist
Award Amount: $69,995.00
Abstract:
Foodborne illnesses of microbial origin continue to be serious food safety problems worldwide, and they also may substantively hamper military operations. Thus, the availability of approaches which significantly reduce contamination of foods with various bacterial pathogens is of paramount… More

Development of a phage-based technology for eliminating or significantly reducing contamination of fruits, vegetables, and red meat with E. coli O157:

Award Year / Program / Phase: 2007 / SBIR / Phase II
Agency / Branch: DOD / ARMY
Principal Investigator: Alexander Sulakvelidze, Chief Scientist
Award Amount: $729,993.00
Abstract:
The availability of approaches which reduce contamination of foods with bacterial pathogens is of paramount importance for ensuring the safety and operational readiness of US troops worldwide, as well as for the safety of civilian populations. Intralytix, Inc., has developed and is already… More

Bacteriophage-based probiotic preparations and their effect on the gut microflora

Award Year / Program / Phase: 2007 / SBIR / Phase I
Agency: HHS
Principal Investigator: Alexander Sulakvelidze
Award Amount: $269,232.00
Abstract:
DESCRIPTION (provided by applicant): The human gastrointestinal (Gl) tract is colonized by an abundant and diverse microbiota. Numerous factors (e.g., antibiotic treatment, diet, etc.) may alter the normal and beneficial bacterial flora of the gut, which m ay lead to various chronic and degenerative… More

Bacteriophage-based probiotic preparation for managing Shigella infections

Award Year / Program / Phase: 2009 / STTR / Phase I
Agency / Branch: DOD / DARPA
Research Institution: University of Florida
Principal Investigator: Alexander Sulakvelidze, Chief Scientist
Award Amount: $99,997.00
RI Contact: Thomas Walsh
Abstract:
Diarrhea remains a major public health challenge worldwide, and it also may significantly hamper US troop operations during combat and peacekeeping missions overseas. Antibiotics can be used to treat diarrheal diseases; however, some foodborne and waterborne bacterial pathogens are developing… More

Bacteriophage therapy for treating A. baumannii infected wounds

Award Year / Program / Phase: 2009 / STTR / Phase I
Agency / Branch: DOD / DARPA
Research Institution: University of Florida
Principal Investigator: Alexander Sulakvelidze, Chief Scientist
Award Amount: $99,991.00
RI Contact: Brian Prindle
Abstract:
Treatment of bacterial-infected wounds is one the most critical problems in modern medicine, and it presents one of the most significant challenges for US troops during combat operations. The management of bacteria in wounds is complicated by the existence of multidrug-resistant strains and… More

Development of phage preparation for managing Salmonella in foods

Award Year / Program / Phase: 2011 / SBIR / Phase I
Agency: USDA
Principal Investigator: Alexander Sulakvelidze, Chief Scientist – (410) 625-2533
Award Amount: $99,984.00
Abstract:
Our project envisions developing a bacteriophage-based product, designated SalmoShield, for eliminating or significantly reducing contamination of poultry products (and eventually other foods) with Salmonella. Salmonellae continue to be one of the leading causes of foodborne disease worldwide,… More

Bacteriophage-based probiotic preparation for managing Shigella infections

Award Year / Program / Phase: 2011 / STTR / Phase II
Agency / Branch: DOD / ARMY
Research Institution: University of Florida
Principal Investigator: Alexander Sulakvelidze, Chief Scientist – (410) 625-2533
Award Amount: $749,969.00
RI Contact: Brian Prindle
Abstract:
During the studies supported by our Phase I STTR grant from the US Army, we began developing and testing a novel concept for a probiotic preparation based on naturally occurring bacteriophages as a way to condition the GI tract"s microflora gently and favorably. The preparation (tentatively… More

Phage preparation for managing Salmonella in foods

Award Year / Program / Phase: 2012 / SBIR / Phase II
Agency: USDA
Principal Investigator: Alexander Sulakvelidze, Chief Scientist – 410-625-2533
Award Amount: $449,865.00
Abstract:
Salmonellae continue to be one of the leading worldwide causes of foodborne bacterial diseases. They cause 1.2-1.4 million annual cases of salmonellosis in the USA, with associated costs estimated to be as high as $12.8 billion/year (in 1998 dollars). Despite continued and escalating efforts to curb… More

Bacteriophages for reducing Vibrio tubiashii associated mortality of shellfish

Award Year / Program / Phase: 2013 / SBIR / Phase I
Agency: USDA
Principal Investigator: Alexander Sulakvelidze, Chief Scientist – 410-625-2533
Award Amount: $99,991.00
Abstract:
This project aims to develop a phage-based product (VTP-100) that will contain a mixture of lytic phages effective against a variety of hatchery strains of Vibrio tubiashii. V. tubiashii is a major cause of larval shellfish mortality, which results in increased costs to the aquaculture industry and… More