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THE LONG TERM OBJECTIVE OF INTRON, INC.

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
1443
Program Year/Program:
1984 / SBIR
Agency Tracking Number:
1443
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Intron Inc.
701 East Bay Street Charleston, SC 29403
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1984
Title: THE LONG TERM OBJECTIVE OF INTRON, INC.
Agency: HHS
Contract: N/A
Award Amount: $49,955.00
 

Abstract:

THE LONG TERM OBJECTIVE OF INTRON, INC. IS TO DEVELOP, MANUFACTURE AND MARKET A PROCUCT LINE OF ANTIGEN/ORGANISM SPECIFIC TRANSFER FACTORS (TF; AN IMMUNE POTENTIATOR) WITH APPLICATION FOR IMMUNOPROPHYLAXIS AND IMMUNOTHERAPY OF A WIDE VARIETY OF HUMAN VETERINARION DISEASES FOR WHICH A STRONG DEPENDENCY ON THE DEVELOPMENT CELL MEDIATED IMMUNITY HAS BEEN DOCUMENTED FOR HOST PROTECTION. TO ACCOMPLISH THIS OBJECTIVE, INTRON, INC. INTENDS TO DEVELOP ORGANISM/ANTIGEN SPECIFIC TRANSFER FACTORS BY IMMUNIZING PREGNANT DAIRY COWS. INTRON, INC. SCIENTISTS HAVE DEMONSTRATED THAT COWS WITH PRE-EXISTING CELLULAR IMMUNE RESPONSIVENESS TO CERTAIN MICROORGANISMS WILL HARBOR TF'S SPECIFIC FOR THESE ORGANISMS IN POST-PARTURITION COLOSTRUM (AND MILK). COLOSTRUM POTENTIALLY REPRESENTS AN INEXPENSIVE RICH SOURCE OF TF. IT IS NOT KNOWN, HOWEVER, WHEN OR BY WHAT ROUTE A COW MUST BE IMMUNIZED IN ORDER TO INDUCE THE ACCUMULATION OF A PARTICULAR ORGANISM SPECIFIC TF IN COLOSTRUM. PHASE I RESEARCH WILL ADDRESS: (A) THE IMMUNIZATION ROUTE TO BE USED, AND (B) THE NUMBER OF IMMUNIZATIONS AND THEIR TEMPORAL RELATIONSHIP TO PARTURITION. IN PHASE II, INTRON, INC. WILL EMPLOY THE INFORMATION OBTAINED FROM PHASE I TO BULK PRODUCE CERTAIN TF'S IN BOVINE'S FOR USE IN DOUBLE-BLIND CLINICAL TRIALS TO DOCUMENT THE EFFICIENCY OF THIS IMMUNE POTENTIATOR IN SELECTED HUMAN AND VETERINARIAN DISEASES WHICH HAVE A MAJOR SOCIO-ECONOMIC IMPACT.

Principal Investigator:

Gregory b. wilson
SENIOR VICE PRESIDENT
0

Business Contact:

Small Business Information at Submission:

Intron Inc.
701 East Bay Street Charleston, SC 29403

EIN/Tax ID:
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No